Results 171 to 180 of about 151,553 (222)

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Density-reducing Jaccard estimators for sketch-based long read applications. [PDF]

BMC Bioinformatics
Rahman T, Kalyanaraman A.
europepmc   +1 more source

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

Synergy and Attenuation of Work-Related Factors in Musculoskeletal Disorders: The Combined Risk Based on Data from the Korean Working Conditions Survey. [PDF]

Medicina (Kaunas)
Lee ES, Kim MH, Kang D, Lee YH, Kim YJ, Kim SY, Kim Y.   +6 more
europepmc   +1 more source

Photothermal Amplification via Nanorobotic Swarming Dynamics

Advanced Science, EarlyView.
This study explores a novel approach to enhance photothermal therapy using magnetically regulated microswarms. It details the development of magnetic nanoparticles organized into dynamic structures that improve heat retention and conversion efficiency.
Qinglong Wang, Lin Su, Zhengxin Yang, Yihang Jiang, Haojin Yang, Qianqian Wang, Li Zhang, Ben Wang, Jiajia Wang   +8 more
wiley   +1 more source

Vibrational spectroscopy, structure and bonding in the family of aluminium-doped niobium clusters, AlNb_<i>n</i>⁺, <i>n</i> = 5-9.

Phys Chem Chem Phys
Singh R, Ferrari P, Pradeep D, Bakker JM, Fielicke A, Janssens E, Lievens P, McGrady JE.   +7 more
europepmc   +1 more source

Assessment of CORA-based levelling osteotomy in the feline stifle: an ex vivo limb press study. [PDF]

Vet Res Commun
Mazdarani P, Miles JE.
europepmc   +1 more source

High‐Performance Multi‐Walled Carbon Nanotubes‐Organic Passivated Si Solar Cells Enabled by Spatially Selective Harvesting of High‐Quality Sponges

Advanced Science, EarlyView.
Our work achieves an efficiency breakthrough in MWCNTs/Si solar cells by screening high‐quality pristine MWCNTs without any separation or purification processes. This breakthrough is mainly attributed to the excellent dispersibility of Nafion and the excellent hole transport property of MWCNTs:Nafion film containing charge transfer doping, passivation,
Yuke Ren, Qi Wang, Jiahe Chen, Jianan Zhang, Jianxin Guo, Dehua Yang, Bingbing Chen, Lu Zhang, Yiming Xu, Xuan Chang, Tiansheng Sun, Qing Gao, Anyuan Cao, Jianhui Chen   +13 more
wiley   +1 more source

Correction: Neonatal microbiota colonization primes maturation of goblet cell-mediated protection in the pre-weaning colon. [PDF]

J Exp Med
Johansson Å, Subramani MV, Yilmaz B, Nyström EEL, Layunta E, Arike L, Sommer F, Rosenstiel P, Vereecke L, Mannerås-Holm L, Wullaert A, Pelaseyed T, Johansson MEV, Birchenough GMH.   +13 more
europepmc   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source