Results 51 to 60 of about 43,958 (304)

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Novel GLDC variants causing nonketotic hyperglycinemia in Chinese patients

Journal of Laboratory Medicine, 2022
Glycine decarboxylase gene (GLDC) mutations cause nonketotic hyperglycinemia (NKH). Patients of NKH usually have heterogeneous phenotypes including respiratory failure, lethargy, myoclonic jerks, and hypotonia. The excessive glycine accumulation in brain
Zhao Xiangyue, Zhang Guoqing, Dong Shumei, Yao Ru-En, Li Niu, Yu Tingting, Bei Fei, Wang Jian   +7 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Avalanches from charged domain wall motion in BaTiO3 during ferroelectric switching

APL Materials, 2020
We report two methods for direct observations of avalanches in ferroelectric materials during the motion of domain walls. In the first method, we use optical imaging techniques to derive changes in domain structures under an electric field.
Blai Casals, Guillaume F. Nataf, David Pesquera, Ekhard K. H. Salje   +3 more
doaj   +1 more source

Relationship between the national universities commission resource allocation parameters used in allocating funds to teaching and learning and research and development and the outcomes of federal universities in Nigeria [PDF]

, 2018
The National Universities Commission Resource Allocation Parameters were developed by the National Universities Commission (NUC), for the allocation of funds to all the federal universities in Nigeria.
Bello Garba, Kofar Sauri
core   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Strong earthquakes and geomagnetic jerks: a cause-effect relationship?

Annals of Geophysics, 1995
Secular variation of the geomagnetic field observed at the Earth's surface has been found to undergo impulsive accelerations Gerks) lasting less than a few years. In this paper the relations between jerks and the occurrence of strong earthquakes (Ms ?
L. Alfonsi, F. Florindo
doaj   +1 more source

Performance Improvement during Attitude Motion of a Vehicle Using Aerodynamic-Surface-Based Anti-Jerk Predictive Controller

Sensors, 2023
This study presents the effectiveness of an anti-jerk predictive controller (AJPC) based on active aerodynamic surfaces to handle upcoming road maneuvers and enhance vehicle ride quality by mitigating external jerks operating on the body of the vehicle ...
Ejaz Ahmad, Iljoong Youn
doaj   +1 more source

Performance analysis of direct N-body algorithms for astrophysical simulations on distributed systems

, 2004
We discuss the performance of direct summation codes used in the simulation of astrophysical stellar systems on highly distributed architectures. These codes compute the gravitational interaction among stars in an exact way and have an O(N^2) scaling ...
Alessia Gualandris, Alfredo Tirado-Ramos, Cohn, Dorband, Foster, Foster, Giersz, Louis, Makino, Makino, Makino, Makino, Makino, Murphy, Plummer, Simon Portegies Zwart   +15 more
core   +1 more source