Results 71 to 80 of about 43,958 (304)

A Case Report of Myoclonus-Dystonia with Isolated Myoclonus Phenotype and Novel Mutation Successfully Treated with Deep Brain Stimulation

Neurology and Therapy, 2020
Introduction Myoclonus-dystonia is an inherited disorder characterized by a combination of myoclonic jerks and dystonia. Mutations in the epsilon-sarcoglycan gene (SGCE) represent the main known genetic cause.
Valentina Besa Lehmann, Marc Rosenbaum, Dennis E. Bulman, Tara Read, Leo Verhagen Metman   +4 more
doaj   +1 more source

The Enhanced Whey Protein Oral Bioavailability and Muscle Anabolism Ability by a Simple and Effective Piperine‐Whey Protein Synergistic Codelivery System

Advanced Science, EarlyView.
WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue, Kaiwen Wu, Bing Wei, Guiling Song, Congyu Sun, Xing Li, Xiangyu Liu, Zhaoxiang Ma, Mingchun Lv, Jasper Landman, Yuan Li   +10 more
wiley   +1 more source

Addiction trends: Internet v casino gambling [PDF]

, 2006
Gambling addictions always result from an interaction and interplay between many factors including the person’s biological and/or genetic predisposition, their psychological constitution, their social environment and the nature of the activity itself ...
Griffiths, M
core  

Nonuniversality in level dynamics

, 1996
Statistical properties of parametric motion in ensembles of Hermitian banded random matrices are studied. We analyze the distribution of level velocities and level curvatures as well as their correlation functions in the crossover regime between three ...
A. Kamenev, A. Pandey, A. Szafer, B. D. Simons, B. D. Simons, C. W. J. Beenakker, C. W. J. Beenakker, D. Braun, D. Saher, F. Haake, F. Izrailev, F. Izrailev, F. von Oppen, G. Casati, G. Casati, G. Casati, H. Bruus, I. Guarneri, J. Goldberg, J. Goldberg, J. Zakrzewski, J. Zakrzewski, J. Zakrzewski, J. Zakrzewski, J. Zakrzewski, Jakub Zakrzewski, K. Z-dotyczkowski, K. Z-dotyczkowski, K. Z-dotyczkowski, K. Z-dotyczkowski, Karol Z-dotyczkowski, M. L. Mehta, M. V. Berry, M. Wilkinson, N. Taniguchi, P. Gaspard, P. Gaspard, P. Seba, Paweł Kunstman, T. Takami, Y. Fyodorov, Y. Fyodorov, Y. V. Fyodorov, Y. V. Fyodorov, Y. V. Fyodorov   +44 more
core   +1 more source

Analytic Study of Grid Star and Reference Star Selection for the Space Interferometry Mission [PDF]

, 2001
Grid stars and reference stars provide the fundamental global and local astrometric reference frames for observations by the Space Interferometry Mission. They must therefore be astrometrically stable at the ~1 uas level.
Gould, Andrew
core   +3 more sources

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

Advanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng, Hainan Wu, Min Liu, Kunpeng Wu, Shuntao Huang, Zulfiqar Ahmed, Lenox Pius, Mengjin Zhu, Dequan Xu   +8 more
wiley   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source

CLINICAL AND GENETIC HETEROGENITY OF JUVENILE MYOCLONIC EPILEPSY

Эпилепсия и пароксизмальные состояния, 2016
The idiopathic generalized epilepsies constitute roughly one-third of all epilepsies. Juvenile myoclonic epilepsy (Janz syndrome) is characterized by myoclonic jerks on awakening, generalized tonic-clonic seizures, and typical absences, with the latter ...
N. A. Shnayder, O. S. Shilkina, K. V. Petrov, I. A. Chernykh, A. V. Diuzhakova   +4 more
doaj   +1 more source

Jeans Instability in a Tidally Disrupted Halo Satellite Galaxy [PDF]

, 2010
We use a hybrid test particle/N-body simulation to integrate 4 million massless test particle trajectories within a fully self-consistent 10^5 particle N-body simulation. The number of massless particles allows us to resolve fine structure in the spatial
Alice C. Quillen, Asphaug, Barnes, Bekki, Binney, Bullock, Carlberg, Dehnen, Fridman, Gaburov, Gnedin, Gomez, Harfst, Helmi, Helmi, Helmi, Helmi, Ibata, Ibata, Johnston, Johnston, Johnston, Johnston, Justin Comparetta, Kaib, Kuijken, Kupper, Kupper, Makino, Makino, Masaki, Mayer, Meza, Minchev, Odenkirchen, Penarrubia, Penarrubia, Purcell, Quillen, Shu, Siegal-Gaskins, Villalobos, Wetzstein, Widrow, Widrow, Yanny   +45 more
core   +1 more source

Evaluation of Experienced Manipulation Characteristics in Robotic Surgery Using Log Data From the Hinotori Surgical System

Annals of Gastroenterological Surgery, EarlyView.
This study analyzed log data from the Japanese hinotori surgical robot to characterize manipulation performed by experienced surgeons in robotic surgery. Compared with less‐experienced surgeons, the experienced group demonstrated shorter task durations, reduced travel distances with the right instrument (Arm3), faster and more dynamically modulated ...
Masaki Saito, Shunsuke Hayakawa, Hiroyuki Sagawa, Tamiaki Kondo, Masanao Ohashi, Sunao Ito, Reo Sato, Hajime Ushigome, Kenta Saito, Ryo Ogawa, Hiroki Takahashi, Shuji Takiguchi   +11 more
wiley   +1 more source