Results 41 to 50 of about 12,196 (160)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Organic Representation as a Critical Media Approach to Leadership Studies in Popular Culture

New Directions for Student Leadership, Volume 2025, Issue 185, Page 75-80, Spring 2025.
ABSTRACT This article applies the critical media concept of organic representation to leadership studies as an analytic of how various creators in popular culture today are not just writing inclusive storytelling but, more notably, modeling new modes of production and self‐presentation that are actively challenging hegemonic industry practices and ...
Raffi Sarkissian
wiley   +1 more source

Genetic basis of human circadian rhythm disorders. [PDF]

, 2013
Circadian rhythm disorders constitute a group of phenotypes that usually present as altered sleep-wake schedules. Until a human genetics approach was applied to investigate these traits, the genetic components regulating human circadian rhythm and sleep ...
Fu, Ying-Hui, Huang, Angela L, Jones, Christopher R, Ptáček, Louis J   +3 more
core   +2 more sources

The neurobiology of circadian rhythms [PDF]

, 2009
Purpose of review There is growing awareness of the importance of circadian rhythmicity in various research fields. Exciting developments are ongoing in the field of circadian neurobiology linked to sleep, food intake, and memory.
Boersma, Gretha J.,, Hut, Roelof A.,, Zee, Eddy A. van der,   +2 more
core   +7 more sources

Refuting causal relations for synchronized pathogen dynamics

Methods in Ecology and Evolution, EarlyView.
Abstract Identifying causal relations is a critical challenge in the study of ecological systems, particularly for studying the spread of pathogens in host populations. Whether dealing with measles in humans, foot and mouth disease in livestock, or white‐nose syndrome in bats—understanding causal relations is essential for understanding the underlying ...
Yair Daon, Kris V. Parag, Amit Huppert, Uri Obolski   +3 more
wiley   +1 more source

Compression‐Expansion: Miniaturization, Modularity, and Logistics Beyond Earth

American Anthropologist, EarlyView.
ABSTRACT If the Cold War space race culminated in a return to Earth, at present we are experiencing a renewed interest in space. Drawing on fieldwork among people working in the space sector in Sweden, this article focuses on some of the imaginaries underpinning this resurgence and the contemporary commercialization of space. Specifically, I hone in on
Chakad Ojani
wiley   +1 more source

The circadian clock, metabolism and obesity [PDF]

, 2017
In the last decades, obesity has been on the rise becoming a burden for health care systems. The reasons behind this rise are most likely caused by lifestyle rather than by an increase in gene mutations, because manifestations of genetic alterations ...
Ando, Arble, Asher, Balsalobre, Bugge, Buxton, Canaple, Chaix, Chappuis, Chavan, Cheifetz, Cho, Cretenet, Dallmann, Dallmann, Damiola, Debruyne, Delezie, Dodd, Dudley, Feillet, Froy, Gachon, Gachon, Garaulet, Gerhart-Hines, Gill, Golombek, Grosbellet, Grosbellet, Guillaumond, Hatori, Hirota, Hirota, Iijima, Ishida, Jakubowicz, Karatsoreos, Kettner, Koike, Kornmann, Kornmann, Kudo, Lamia, Le Minh, Li, Marcheva, Mattson, Mitsui, Mohawk, Montagner, Mukherji, Mukherji, Nader, Nakahata, Oike, Oike, Oster, Ouyang, Pan, Panda, Partch, Perelis, Pitts, Preitner, Punjabi, Ramkisoensing, Ramsey, Rudic, Salgado-Delgado, Sans-Fuentes, Sato, Schibler, Schmutz, Sherman, So, Spoelstra, Stephan, Stephan, Storch, Tsai, Turek, Varga, Wahli, Weitzman, Yang, Zarrinpar, Zhang, Zwighaft   +88 more
core   +1 more source

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang, Anni Ling, Poemen P. Chan, Jason C. Yam, Chi Pui Pang, Clement C. Tham, Li Jia Chen   +6 more
wiley   +1 more source

Recent advances in multimodality imaging‐guided therapy in pericarditis

European Journal of Clinical Investigation, EarlyView.
Multiple imaging targets have been identified as essential biomarkers to confirm pericardial thickening, edema, neovascularization, inflammation, fibrosis/calcification, cardiac tamponade physiology, and constriction. This novel approach is called imaging‐guided therapy, which guides anti‐inflammatory therapy, assesses treatment response, assists in ...
Joseph El Roumi, Aldo L. Schenone, Paul Cremer, Tom Kai Ming Wang, Allan Klein   +4 more
wiley   +1 more source

Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock

The FEBS Journal, EarlyView.
Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány, Anita Szőke, Aladár Pettkó‐Szandtner, Eszter Éva Kálmán, Michael Brunner, Norbert Gyöngyösi, Krisztina Káldi   +6 more
wiley   +1 more source