Results 71 to 80 of about 20,996 (176)

Targeting Cryptochromes in Chronic Diseases

Cell Biology International, Volume 49, Issue 12, Page 1579-1590, December 2025.
ABSTRACT The circadian clock generates 24‐h molecular rhythms through transcription–translation negative feedback loops (TTFLs) and regulates daily physiological processes such as sleep–wake cycles, body temperature, hormone secretion, metabolism, and immune function.
Takuro Toda, Tsuyoshi Hirota
wiley   +1 more source

Early in‐hospital treatment of acute heart failure. Part 2 of the international expert opinion series on AHF management

ESC Heart Failure, Volume 12, Issue 6, Page 3826-3843, December 2025.
This state‐of‐the‐art review outlines a practical, evidence‐based framework for early acute heart failure management to address critical gaps in current guidance and improve early treatment outcomes. Key components include early identification of co‐existing conditions, bedside haemodynamic profiling, a structured diagnostic approach incorporating both
Anika S. Naidu, Andrew P. Ambrosy, Gad Cotter, Edimar A. Bocchi, Javed Butler, Ovidiu Chioncel, Beth Davison, Anastase Dzudie, Yonathan Freund, Marat Fudim, Sivadasanpillai Harikrishnan, Ivna G. Cunha, Alexandre Mebazaa, Robert J. Mentz, Òscar Miró, Siti E. Nauli, Mateo Pagnesi, Naoki Sato, Gianluigi Savarese, Karen Sliwa‐Hahnle, Yuhui Zhang, Jingmin Zhou, Jan Biegus   +22 more
wiley   +1 more source

The Brain-Gut-Microbiome Axis. [PDF]

, 2018
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir, Martin, Clair R, Mayer, Emeran A, Osadchiy, Vadim   +3 more
core   +2 more sources

Wearable biosensors based on molecularly imprinted polymers

FlexMat, Volume 2, Issue 4, Page 475-492, December 2025.
Wearable biosensors based on molecularly imprinted polymers (MIPs) provide real‐time, non‐invasive monitoring of key biomarkers. This review highlights the research advances on MIPs‐based biosensors with enhanced selectivity, stability, and adaptability in flexible sensing platforms.
Xiangnan Li, Rongqi Ou, Zhen Yuan, Yuanjing Lin   +3 more
wiley   +1 more source

Rodent models for the analysis of tissue clock function in metabolic rhythms research [PDF]

, 2017
The circadian timing system consists on a distributed network of cellular clocks that together coordinate 24-h rhythms of physiology and behavior. Clock function and metabolism are tightly coupled, from the cellular to the organismal level.
Astiz, Mariana, Leinweber, Brinja, Oster, Henrik, Tsang, Anthony H.   +3 more
core   +2 more sources

Nutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This review highlights the growing evidence linking diet and key nutrients with sleep quality and circadian regulation. Nutrients such as tryptophan, magnesium, and omega‐3 fatty acids, along with dietary patterns like the Mediterranean and plant‐based diets, demonstrate positive associations with sleep duration and efficiency.
Rony Abou‐Khalil
wiley   +1 more source

Obesity and sleep disturbance: the chicken or the egg? [PDF]

, 2018
Epidemiological studies suggested an association between obesity and sleep disturbances. Obstructive sleep apnea is the most prevalent type of obesity-related sleep disorder that lead to an increased risk for numerous chronic health conditions.
Annunziata, G, Barrea, L, Colao, A, Di Somma, C, Laudisio, D, Muscogiuri, G, Savastano, S.   +6 more
core   +1 more source

A high-light therapy restores the circadian clock and corrects the pathological syndrome generated in restricted-fed mice

Proceedings of the National Academy of Sciences of the United States of America
Significance Disruption of the circadian rhythms (i.e., misalignment between the suprachiasmatic nucleus circadian clock (SCNCC) and the peripheral CCs (PCC’s) is at the origin of pathologies in mice under restricted feeding (RF). It remains to establish
Manohar Damara, Nisha Misra, Pierre Chambon   +2 more
semanticscholar   +1 more source

Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts [PDF]

, 2017
The circadian clock regulates metabolic homeostasis and its disruption predisposes to obesity and other metabolic diseases. However, the effect of phase shifts on metabolism is not completely understood.
Cambras Riu, Trinitat, Crhistiane Andressa da Silva, Díez Noguera, Antoni, Herrero Rodríguez, Laura, Serra i Cucurull, Dolors, Valcarcel-Jimenez, Lorea   +5 more
core   +1 more source

Sleep disorders, sleepiness and traffic safety: a public health menace [PDF]

, 2006
Sleep disorders are not uncommon and have been widely reported throughout the world. They have a profound impact on industrialized 24-h societies. Consequences of these problems include impaired social and recreational activities, increased human errors,
Kayumov, Leonid, Lowe, Alan D., Mello, Marco Tulio de, Pandi-Perumal, Seithikurippu Ratnas, Pires, Maria Laura Nogueira, Santana, Marcos Gonçalves de, Tufik, Sergio, Verster, Joris C.   +7 more
core   +1 more source