Results 61 to 70 of about 5,503 (225)

Sevoflurane-medicated the pathway of chemokine receptors bind chemokines in patients undergoing CABG

Open Life Sciences, 2017
We aim to identify sevoflurane-induced modules and pathways in patients following coronary artery bypass graft (CABG) surgery, and to further elucidate the molecular mechanisms of the cardioprotective effects of sevoflurane.
Kong Bing, Ma Yu-Wu, Li De-Xue, Liu Xi-Jiang, Xu Yong-Guang   +4 more
doaj   +1 more source

Clinical practice guidelines for gene therapy to treat hereditary hearing loss

Interdisciplinary Medicine, Volume 2, Issue 2, April 2024.
Abstract Hereditary deafness is a common neurosensory disorder, and 148 non‐syndromic deafness genes have been identified to date. Gene therapy has been used to treat a variety of genetic diseases, but no gene therapy drug for hereditary deafness has been approved for clinical use.
Jieyu Qi, Fangzhi Tan, Liyan Zhang, Ling Lu, Hongyang Wang, Wenyan Li, Wenwen Liu, Xiaolong Fu, Zuhong He, Xiaoqiong Ding, Shan Sun, Qiaojun Fang, Yaodong Dong, Xuewei Zhu, Busheng Tong, Xianbao Cao, Min Guo, Xinmiao Fan, Qin Wang, Lu Ma, Tianhong Zhang, Yafeng Yu, Yongxin Li, Jiangang Fan, Yong Cui, Peina Wu, Hongzheng Zhang, Jie Tang, Weiwei Guo, Dingjun Zha, Fanglei Ye, Shuangba He, Wei Cao, Jianming Yang, Xiaoyun Qian, Yu Zhao, Jingwu Sun, Xiaowei Chen, Yu Sun, Ming Xia, Qiuju Wang, Huijun Yuan, Yong Feng, Weijia Kong, Shiming Yang, Haibo Wang, Maoli Duan, Xia Gao, Huawei Li, Lei Xu, Renjie Chai   +50 more
wiley   +1 more source

High lymphocyte signature genes expression in parathyroid endocrine cells and its downregulation linked to tumorigenesisResearch in context

EBioMedicine
Summary: Background: To date, because of the difficulty in obtaining normal parathyroid gland samples in human or in animal models, our understanding of this last-discovered organ remains limited.
Chong Geng, Junjun Liu, Bingzhou Guo, Kailin Liu, Pengfei Gong, Bao Wang, Qiang Wan, Liang Sun, Jiajun Zhao, Yongfeng Song   +9 more
doaj   +1 more source

Mitochondrial damage‐associated molecular patterns: A new insight into metabolic inflammation in type 2 diabetes mellitus

Diabetes/Metabolism Research and Reviews, Volume 40, Issue 2, February 2024.
Abstract The pathogenesis of diabetes is accompanied by increased levels of inflammatory factors, also known as “metabolic inflammation”, which runs through the whole process of the occurrence and development of the disease. Mitochondria, as the key site of glucose and lipid metabolism, is often accompanied by mitochondrial function damage in type 2 ...
Yan Wang, Jingwu Wang, Si‐Yu Tao, Zhengting Liang, Rong xie, Nan‐nan Liu, Ruxue Deng, Yuelin Zhang, Deqiang Deng, Guangjian Jiang   +9 more
wiley   +1 more source

Akulturasi Unsur Kungfu Tiongkok dalam Pencak Silat Betawi [PDF]

, 2015
This study aimed to examine the influence of acculturation of Chinese Kungfu elements on Pencak Silat Betawi. The study used qualitative method and observation with interview and literature study by looking up Betawi and Pencak Silat on Batavia ...
Khosasih, A. (Andyni), Lim, S. (Sugiato), Sufianto, A. (Agustinus)   +2 more
core   +2 more sources

Duck pan‐genome reveals two transposon insertions caused bodyweight enlarging and white plumage phenotype formation during evolution

iMeta, Volume 3, Issue 1, February 2024.
We present the first duck pan‐genome constructed using five genome assemblies capturing ∼40.98 Mb new sequences absent from the reference genome. We find a significant portion of the detected structural variants were derived from transposable element (TE) activity.
Kejun Wang, Guoying Hua, Jingyi Li, Yu Yang, Chenxi Zhang, Lan Yang, Xiaoyu Hu, Armin Scheben, Yanan Wu, Ping Gong, Shuangjie Zhang, Yanfeng Fan, Tao Zeng, Lizhi Lu, Yanzhang Gong, Ruirui Jiang, Guirong Sun, Yadong Tian, Xiangtao Kang, Haifei Hu, Wenting Li   +20 more
wiley   +1 more source

Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

Oncogene, 2016
Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By using label-free Raman spectromicroscopy, we found an aberrant accumulation
Junjie Li, D. Gu, Seung Young Lee, B. Song, S. Bandyopadhyay, Samuel Chen, S. F. Konieczny, Timothy Ratliff, Xiaoben Liu, Jingwu Xie, Ji‐Xin Cheng   +10 more
semanticscholar   +1 more source

Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas [PDF]

, 2017
The Hedgehog (Hh) pathway is critical for cell differentiation, tissue polarity, and stem cell maintenance during embryonic development, but is silent in adult tissues under normal conditions. However, aberrant Hh signaling activation has been implicated
Jain, Sachin, Song, Ruolan, Xie, Jingwu
core   +2 more sources

Morpho-Molecular and Ultrastructural Characterization of Discocriconemella parasinensis n. sp. from Zhejiang Province, China

Journal of Nematology, 2022
During a recent inventory survey of the nematofauna of tea plantation at Zhejiang Province, China, Discocriconemella parasinensis n. sp. was detected in the rhizosphere of Camellia sinensis.
Li Junxia, Munawar Maria, Castillo Pablo, Zheng Jingwu   +3 more
doaj   +1 more source

Association between Glycosylated Hemoglobin and Serum Uric Acid: A US NHANES 2011–2020

International Journal of Endocrinology, Volume 2024, Issue 1, 2024.
Background. Serum uric acid (SUA) and glycosylated hemoglobin (HbA1c) were closely related to the body’s metabolism. This study aimed to investigate the relationship between HbA1c and SUA in adults. Methods. This study selected 7293 participants aged ≥20 from 2011 to 2020 in the National Health and Nutrition Examination Survey (NHANES).
Huan Li, Mingliang Sun, Chengcheng Huang, Jingwu Wang, Yanqin Huang, Arturo Bevilacqua   +5 more
wiley   +1 more source