Results 71 to 80 of about 210,325 (286)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Occupational biomechanical risk factors for surgically treated ulnar nerve entrapment in a prospective study of male construction workers

Scandinavian Journal of Work, Environment & Health, 2019
OBJECTIVES: The aim of this study was to determine the association between occupational biomechanical exposures and occurrence of surgically treated ulnar nerve entrapment (UNE).
Jennie A Jackson, David Olsson, Laura Punnett, Alex Burdorf, Bengt Järvholm, Jens Wahlström   +5 more
doaj   +1 more source

Mesothelioma in Sweden: Dose–Response Analysis for Exposure to 29 Potential Occupational Carcinogenic Agents

Safety and Health at Work, 2018
Background: There is little information on the dose–response relationship between exposure to occupational carcinogenic agents and mesothelioma. This study aimed to investigate this association as well as the existence of agents other than asbestos that ...
Nils Plato, Jan I. Martinsen, Kristina Kjaerheim, Pentti Kyyronen, Pär Sparen, Elisabete Weiderpass   +5 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Analysis of mortality in a pooled cohort of Canadian and German uranium processing workers with no mining experience. [PDF]

, 2017
PurposeLong-term health risks of occupational exposures to uranium processing were examined to better understand potential differences with uranium underground miners and nuclear reactor workers.MethodsA cohort study of mortality of workers from Port ...
Fenske, Nora, Kreuzer, Michaela, Laurier, Dominique, Schnelzer, Maria, Zablotska, Lydia B, Zhivin, Sergey   +5 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

The effectiveness of the international strategy in the analysis of the political language: Berlusconi´s speech at the chamber of deputies on the 13TH May 2008 [PDF]

, 2017
In this context we will oversee to understand if and in which measure, the intentional attitude delineated today by the school of Anglo-Saxon thought and, in particular, by Dennett’s philosophy, can constitute an opportune and effective instrument for ...
Bermúdez Vázquez, Manuel (Coordinador), Intorre, Dario, Macho Reyes, Rafael Diego (Coordinador)   +2 more
core  

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M. Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source

Application of Raman and Photoluminescence Spectroscopy to MgO‐C Refractories

Advanced Engineering Materials, EarlyView.
Visible to near infrared luminescence of MgO is studied on MgO‐C bricks and nominally pure MgO powder, with focus on two similar sharp high‐intensity signals, at 699 and 871 nm, each surrounded by symmetrical sidebands. The nature of these sidebands is investigated by temperature‐dependent spectroscopic measurements, confirming phonon involvement by ...
Julia Richter, Felix Drechsler, Till M. J. Stadtmüller, Cameliu Himcinschi, Christos G. Aneziris, Jens Kortus   +5 more
wiley   +1 more source

Providing Feedback Following Leadership Walkrounds is Associated with Better Patient Safety Culture, Higher Employee Engagement and Lower Burnout [PDF]

, 2017
Background There is a poorly understood relationship between Leadership WalkRounds (WR) and domains such as safety culture, employee engagement, burnout and work-life balance.
Adair, Kathryn C., Bogan, Brittany, Frankel, Allan S., Frankel, Terru Christensen, Jamal, Maleek, Leonard, Michael W., Magnus, Brooke E., Proulx, Joshua, Schwendimann, Rene, Sexton, J. Bryan, Watson, Sam R.   +10 more
core   +2 more sources