Results 101 to 110 of about 725,265 (297)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Technology Shocks and Job Flows

open access: green, 2007
Claudio Michelacci   +1 more
openalex   +2 more sources

Caracterización sociodemográfica y de salud vocal de docentes universitarios en Bogotá D.C., Colombia Sociodemographic characterization and the vocal health of university teachers in Bogotá D.C., Colombia

open access: yesRevista Cubana de Higiene y Epidemiología, 2011
El desempeño de las labores diarias expone a los docentes a diversos factores de riesgo que pueden desencadenar diversos problemas de salud. OBJETIVO: caracterizar las condiciones de salud vocal-trabajo de algunos docentes de una Universidad Pública de ...
Lady Catherine Cantor Cutiva   +1 more
doaj  

The Effect of Work Motivation and Teamwork on Employee Performance with Job Satisfaction as an Intervening Variable in Asahan District Office

open access: yesEl-Jizya: Jurnal Ekonomi Islam
Employee performance is a strategic determinant of an organization's effectiveness and sustainability, especially in government institutions that have the primary mandate to deliver public services. At the Public Works and Spatial Planning Office (PUTR)
Haris Winanda Sebayang   +2 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

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