Results 61 to 70 of about 2,676,565 (309)
Ecosystem restoration job creation potential in Brazil
People and Nature, 2022 The central motivation to restore ecosystems at a planetary scale has been to reverse degradation and provide multiple environmental benefits, but key global players like governments may be more interested in social outcomes from undertaking restoration,
Pedro H. S. Brancalion +11 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 2020 De JOB-monitor is in 2001 door Jongeren Organisatie Beroepsonderwijs (JOB) opgezet om de tevredenheid van mbo-studenten te meten. Elke twee jaar laat JOB de monitor uitvoeren door onderzoeksbureau ResearchNed.
ResearchNed
core +2 more sources
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Job Creation and Destruction in Northern Ireland - 1973-1993 [PDF]
Job creation and destruction estimates are made for Northern Ireland manufacturing using the ARD database. International comparisons suggest job creation and destruction rates in Northern Ireland were below those elsewhere. Job turnover rates exhibit the
Stephen Roper
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
An Ecosystem-Based Job-Creation Engine Fuelled by Technology Entrepreneurs [PDF]
Technology Innovation Management Review, 2013 Job creation is at the centre of the rationale provided by governments and publicly funded organizations for investing in services purported to support entrepreneurs to launch and grow technology startups. However, little is known about how to design and
Sonia D. Bot, Tony Bailetti
doaj
Why Is Multinational Status Important? Evidence from Job Creation and Job Destruction in Japan [PDF]
Previous studies of job creation and job destruction (JCJD) have found that the gross job reallocation rate greatly exceeded the net job creation rate even in a narrowly defined industry or the same international trade orientation.
Toshiyuki Matsuura, Kozo Kiyota
core