Results 61 to 70 of about 1,250,588 (296)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
J@ti Undip: Jurnal Teknik Industri, 2018 Abstrak Proses produksi ST 37777 di PT Ebako Nusantara menggunakan jadwal yang didasarkan oleh proses-proses yang dilakukan dengan menggunakan data historis yang telah ada dari proses produksi yang telah dilakukan.
Mellysa Asmawar, Sriyanto Sriyanto
doaj +1 more source
Scheduling Interviews for a Job Fair [PDF]
Operations Research, 1990 We describe the design and use of a program to schedule interviews for law firms and students at a job fair. It has been used to manage the Southeastern Public Interest Job Fair for the last six years. The program uses a new scheduling algorithm that produces particularly convenient schedules.
John J. Bartholdi III, Kevin L. McCroan
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Trust-driven job scheduling heuristics for computing grid
Tongxin xuebao, 2006 Currently existing grid scheduling algorithms largely ignore the impact of trust mechanism,which made their applicability in a realistic environment rather doubtful.Based on the grid trust model and trust utilization functions,a trust-driven grid job ...
ZHANG Wei-zhe1 +5 more
doaj +2 more sources
Research on Multi-Criteria Scheduling Strategies for Kubernetes Heterogeneous Clusters [PDF]
Jisuanji gongchengThe efficient utilization of resources across nodes in a heterogeneous cluster is pivotal for enhancing the overall resource utilization of the cluster.
SUN Guifa, SUN Jianpeng, XIE Xiguo
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A Modified Multi-Step Crossover Fusion (MSXF) In Solving Some Deterministic Job Shop Scheduling Problem (JSSP) [TS157.5. M214 2008 f rb]. [PDF]
, 2008 This thesis addresses the job shop scheduling problem (JSSP) with the objective of minimising the makespan value. Tesis ini membincangkan masalah penskedulan kerja kedaian (JSSP) dengan objektif untuk meminimumkan masa ...
Omar, Mahanim
core +1 more source
Job Scheduling Management Research of Intelligent Manufacturing Based on the Internet of Things
Chemical Engineering Transactions, 2015 In-depth and detailed requirements of intelligent manufacturing are analyzed for the virtual cloud enterprise, and it is explained that the process of the main task of job scheduling about intelligent manufacturing based on Internet of things.
G.R. Li, Y.F. Ge, Y.X. Wang, S.P. Hu
doaj +1 more source