Results 81 to 90 of about 1,250,588 (296)

Better approximation guarantees for job-shop scheduling [PDF]

open access: yes
Job-shop scheduling is a classical NP-hard problem. Shmoys, Stein and Wein presented the first polynomial-time approximation algorithm for this problem that has a good (polylogarithmic) approximation guarantee.
Paterson, Michael S.   +3 more
core  

PENYELESAIAN MASALAH JOB SHOP MENGGUNAKAN ALGORITMA GENETIKA

open access: yesJurnal Masyarakat Informatika, 2010
Job Shop Scheduling Problem (JSP) is a problem of work scheduling that can be describe by one or several job that have to be done by one or several source, each job contain of several operation that has to be done without interuption in several time and ...
Satriyo Adhy, Kushartantya Kushartantya
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Flexible job shop scheduling using genetic algorithm and heuristic rules

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
Job shop scheduling with the availability of more than one machine to perform an operation, also known as the flexible job shop scheduling problem, is computationally NP-hard.
Parinya KAWEEGITBUNDIT, Toru EGUCHI
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A branch-and-bound algorithm for stable scheduling in single-machine production systems. [PDF]

open access: yes
Robust scheduling aims at the construction of a schedule that is protected against uncertain events. A stable schedule is a robust schedule that will change little when variations in the input parameters arise.
Herroelen, Willy, Leus, Roel
core  

Greedy Firefly Algorithm for Optimizing Job Scheduling in IoT Grid Computing. [PDF]

open access: yesSensors (Basel), 2022
Yousif A   +6 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Meta-heuristics for stable scheduling on a single machine. [PDF]

open access: yes
This paper presents a model for single-machine scheduling with stability objective and a common deadline. Job durations are uncertain, and our goal is to ensure that there is little deviation between planned and actual job starting times.
Ballestin, F, Leus, Roel
core  

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