Results 121 to 130 of about 1,901,812 (345)

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro   +12 more
wiley   +1 more source

MODEL OPTIMASI PENJADWALAN PRODUKSI YANG TERINTEGRASI DENGAN MEMPERTIMBANGKAN FAKTOR BIAYA

open access: yesJurnal Teknik Industri, 2003
The paper discusses optimation integrated production scheduling model which is included deciding production allocation, operations regulating for job shop process and capacity planning as integrated activity.
Dian Retno Sari Dewi
doaj  

Transgenic Algorithm Applied to the Job Shop Rescheduling Problem

open access: yesIngeniería
Context: Job sequencing has been approached from a static perspective, without considering the occurrence of unexpected events that might require modifying the schedule, thereby affecting its performance measures.
Néstor Andrés Beltrán-Bernal   +2 more
doaj   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu   +13 more
wiley   +1 more source

Solving flexible job shop scheduling using genetic algorithm [PDF]

open access: yes, 2013
This work addresses a real assembly cell: the AIP-PRIMECA cell at the Université e de Valenciennes et du Hainaut-Cambrésis, in France. This system can be viewed as a Flexible Job Shop, leading to the formulation of a Flexible Job Shop Scheduling Problem (
Barbosa, José   +3 more
core  

Remaining Burden of Spinal Muscular Atrophy Among Treated Patients: A Survey of Patients and Caregivers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons   +8 more
wiley   +1 more source

Particle swarm optimization applied to job shop scheduling [PDF]

open access: yes, 2007
In this project we have to apply the particle swarm optimization algorithm to job shop scheduling problem. Job shop scheduling is a combinatorial optimization problem where we have to arrange the jobs which may or may not be processed in every machine in
Dwivedi , Piyush, Vishal , Vivek
core  

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó   +17 more
wiley   +1 more source

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