Results 31 to 40 of about 23,175 (311)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Optimal job insertion in the no-wait job shop [PDF]
Journal of Combinatorial Optimization, 2012 The no-wait job shop (NWJS) considered here is a version of the job shop scheduling problem where, for any two operations of a job, a fixed time lag between their starting times is given. Also, sequence-dependent set-up times between consecutive operations on a machine can be present.
Bürgy, Reinhard, Gröflin, Heinz
openaire +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Matrix: Jurnal Manajemen Teknologi dan Informatika, 2016 Job shop atau yang dikenal juga dengan istilah shop floor control merupakan salah satu metode penyusunan jadwal produksi yang rumit. Beberapa faktor penyebab rumitnya penyusunan jadwal menggunakan metode job shop adalah banyaknya jumlah variasi produk ...
Ida Bagus Putra Manuaba
doaj
The Effects of Machine Load Sitnations on Performance of Job Shop and Group Scheduling
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 1998 Perfonnance of job shop and group scheduling ndermultinatch work input environment was exarnined against two nachine load (light and high load) situations.
O.TORKUL TORKUL
doaj +1 more source
Dynamic Data Scheduling of a Flexible Industrial Job Shop Based on Digital Twin Technology
Discrete Dynamics in Nature and Society, 2022 Aiming at the problems of premature convergence of existing workshop dynamic data scheduling methods and the decline in product output, a flexible industrial job shop dynamic data scheduling method based on digital twin technology is proposed.
Juan Li, Xianghong Tian, Jing Liu
doaj +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Research on steady-state simulation in dynamic job shop scheduling problem
Advances in Mechanical Engineering, 2015 A systematic research of steady state for the dynamic job shop scheduling problem with jobs releasing continuously over time has been conducted in this article.
Hegen Xiong +3 more
doaj +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
On the Job-Shop Scheduling Problem [PDF]
Operations Research, 1960 This is a proposal for the application of discrete linear programming to the typical job-shop scheduling problem—one that involves both sequencing restrictions and also noninterference constraints for individual pieces of equipment. Thus far, no attempt has been made to establish the computational feasibility of the approach in the case of large-scale
openaire +2 more sources