Results 61 to 70 of about 737,186 (350)
A case study of process facility optimization using discrete event simulation and genetic algorithm [PDF]
, 2005 Optimization problems such as resource allocation, job-shop scheduling, equipment utilization and process scheduling occur in a broad range of processing industries.
Burt, G.M. +4 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Capacity Planning and Leadtime management [PDF]
, 1996 In this paper we discuss a framework for capacity planning and lead time management in manufacturing companies, with an emphasis on the machine shop. First we show how queueing models can be used to find approximations of the mean and the variance of ...
Buitenhek, R., Zijm, W.H.M.
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Job Shop Scheduling Under Uncertainty
, 2022 In this research we aim to investigate the job shop scheduling problem with uncertain processing times. First we study the literature for the best solution approaches for the deterministic job shop problem. Among all developed algorithms in the literature the famous TSAB algorithm by Nowicki and Smutnicki in 1996 has shown well performance regarding ...
Ghorbani Saber, Reza +3 more
openaire +2 more sources
Job shop control:in search of the key to delivery improvements [PDF]
, 2015 The last major performance breakthroughs in job shop control stem from the 1980s and 1990s. We generate a new search direction for designing job shop control policies, providing a key to delivery improvements.
Gaalman, Gerard J. C. +3 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Dynamic Data Scheduling of a Flexible Industrial Job Shop Based on Digital Twin Technology
Discrete Dynamics in Nature and Society, 2022 Aiming at the problems of premature convergence of existing workshop dynamic data scheduling methods and the decline in product output, a flexible industrial job shop dynamic data scheduling method based on digital twin technology is proposed.
Juan Li, Xianghong Tian, Jing Liu
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Entre Ciencia e Ingeniería, 2018 En el presente artículo se aborda el problema Flexible Job Shop Scheduling (FJSSP) con restricciones de transporte, con el objetivo de minimizar el makespan realizando la secuenciación y asignación de máquinas. Se llevó a cabo una revisión bibliográfica
Tatiana Andrea Castillo Jaimes +4 more
doaj +1 more source