Results 71 to 80 of about 199,857 (394)

Semi-autonomous Intersection Collision Avoidance through Job-shop Scheduling [PDF]

open access: yes, 2015
In this paper, we design a supervisor to prevent vehicle collisions at intersections. An intersection is modeled as an area containing multiple conflict points where vehicle paths cross in the future. At every time step, the supervisor determines whether
Bussieck M. R.   +6 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Job Shop Scheduling by Local Search [PDF]

open access: yesINFORMS Journal on Computing, 1996
We survey solution methods for the job shop scheduling problem with an emphasis on local search. Both deterministic and randomized local search methods as well as the proposed neighborhoods are discussed. We compare the computational performance of the various methods in terms of their effectiveness and efficiency on a standard set of problem ...
Vaessens, R. J. M.   +2 more
openaire   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Analysis of usage of genetic and tabu search algorithms in shop scheduling

open access: yesLietuvos Matematikos Rinkinys, 2008
A wide area of scheduling problem is industrial so-called shop scheduling (Job Shop, Flow Shop and Open Shop) which has important applications in real world industrial problems.
Edgaras Šakurovas   +1 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Job-shop scheduling with limited capacity buffers [PDF]

open access: yes, 2006
In this paper we investigate job-shop problems where limited capacity buffers to store jobs in non-processing periods are present. In such a problem setting, after finishing processing on a machine, a job either directly has to be processed on the ...
Brucker, Peter   +3 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

An effective hybrid algorithm for multi-objective flexible job-shop scheduling problem

open access: yesAdvances in Mechanical Engineering, 2018
Genetic algorithm is one of primary algorithms extensively used to address the multi-objective flexible job-shop scheduling problem. However, genetic algorithm converges at a relatively slow speed.
Xiabao Huang, Zailin Guan, Lixi Yang
doaj   +1 more source

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