Results 21 to 30 of about 5,358,464 (305)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Mag deur taal in 1 Johannes

open access: yesHTS Teologiese Studies/Theological Studies, 2012
Power through language in 1 John. Power is often exercised through language. Here it is argued that the author of John utilises different language strategies in order to exert power over and to influence his intended readers.
Jan G. van der Watt
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Letter from John Lennon to Hagan

open access: yes, 1928
Holograph letter from John Lennon, the Presbytery, Portarlington (County Laois), to Hagan, enclosing copy typescript will and probate of Fr. Matthew Lawlor, Portarlington (Solicitor John Foley); appointing Frs. M. Cullen and L.J. Kehoe executors; leaving

core   +2 more sources

“… God Said”: Toward a Quantum Theology of Creation

open access: yesOpen Theology
This work argues that because Quantum Mechanics (QM) is superb at simulating natural, physical phenomena, so-called quantum-native phenomena, and that Quantum Natural Language Processing (QNLP), its child, is also quantum-native, God’s generative ...
Walton Ryder Dale
doaj   +1 more source

Ethical Principles of “Abiding In” from John’s Perspective

open access: yesDiligentia: Journal of Theology and Christian Education
Johannine Literature is known for its rich theological perspective. Grounding from his theological standpoints, he draws his ethical principles. One of the disputes in this book is whether John has explicit or implicit ethical implications for his ...
Cathryne Berliana Nainggolan
doaj   +1 more source

New challenges in diagnosis of haemoglobinopathies: Migration of populations

open access: yesThalassemia Reports, 2018
The current influx of economic migrants and asylum seekers from countries with a high prevalence of haemoglobinopathies creates new challenges for health care systems and diagnostic laboratories.
John Old   +11 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

John Little John [PDF]

open access: yesScientific American
n ...
openaire   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

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