Results 1 to 10 of about 1,014,012 (185)
Skin cancer screening: recommendations for data-driven screening guidelines and a review of the US Preventive Services Task Force controversy
Melanoma Management, 2017 Melanoma is usually apparent on the skin and readily detected by trained medical providers using a routine total body skin examination, yet this malignancy is responsible for the majority of skin cancer-related deaths.Mariah M Johnson, Sancy A Leachman, Lisa G Aspinwall, Lee D Cranmer, Clara Curiel-Lewandrowski, Vernon K Sondak, Clara E Stemwedel, Susan M Swetter, John Vetto, Tawnya Bowles, Robert P Dellavalle, Larisa J Geskin, Douglas Grossman, Kenneth F Grossmann, Jason E Hawkes, Joanne M Jeter, Caroline C Kim, John M Kirkwood, Aaron R Mangold, Frank Meyskens, Michael E Ming, Kelly C Nelson, Michael Piepkorn, Brian P Pollack, June K Robinson, Arthur J Sober, Shannon Trotter, Suraj S Venna, Sanjiv Agarwala, Rhoda Alani, Bruce Averbook, Anna Bar, Mirna Becevic, Neil Box, William E Carson, Pamela B Cassidy, Suephy C Chen, Emily Y Chu, Darrel L Ellis, Laura K Ferris, David E Fisher, Kari Kendra, David H Lawson, Philip D Leming, Kim A Margolin, Svetomir Markovic, Mary C Martini, Debbie Miller, Debjani Sahni, William H Sharfman, Jennifer Stein, Alexander J Stratigos, Ahmad Tarhini, Matthew H Taylor, Oliver J Wisco, Michael K Wong +55 moredoaj +2 more sourcesA Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with BRAF-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation. [PDF]
Cancer DiscovA phase I trial with an alternative, pharmacokinetics-informed dose escalation design demonstrated that a brain-penetrant, selective, pan-mutant BRAF inhibitor could overcome resistance to approved BRAF inhibitors in BRAF-mutant cancers.Yaeger R, McKean MA, Haq R, Beck JT, Taylor MH, Cohen JE, Bowles DW, Gadgeel SM, Mihalcioiu C, Papadopoulos KP, Diamond EL, Sturtz KB, Feng G, Drescher SK, Reddy MB, Sengupta B, Maity AK, Brown SA, Singh A, Brown EN, Baer BR, Wong J, Mou TC, Wu WI, Kahn DR, Gadal S, Rosen N, Gaudino JJ, Lee PA, Hartley DP, Rothenberg SM. +30 moreeuropepmc +2 more sourcesAuthor Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration [PDF]
Nature CommunicationsSarah Opie-Martin, Alfredo Iacoangeli, Simon D. Topp, Olubunmi Abel, Keith Mayl, Puja R. Mehta, Aleksey Shatunov, Isabella Fogh, Harry Bowles, Naomi Limbachiya, Thomas P. Spargo, Ahmad Al-Khleifat, Kelly L. Williams, Jennifer Jockel-Balsarotti, Taha Bali, Wade Self, Lyndal Henden, Garth A. Nicholson, Nicola Ticozzi, Diane McKenna-Yasek, Lu Tang, Pamela J. Shaw, Adriano Chio, Albert Ludolph, Jochen H. Weishaupt, John E. Landers, Jonathan D. Glass, Jesus S. Mora, Wim Robberecht, Philip Van Damme, Russell McLaughlin, Orla Hardiman, Leonard van den Berg, Jan H. Veldink, Phillippe Corcia, Zorica Stevic, Nailah Siddique, Vincenzo Silani, Ian P. Blair, Dong-sheng Fan, Florence Esselin, Elisa de la Cruz, William Camu, Nazli A. Basak, Teepu Siddique, Timothy Miller, Robert H. Brown, Ammar Al-Chalabi, Christopher E. Shaw +48 moredoaj +2 more sourcesRetroSnake: A modular pipeline to detect human endogenous retroviruses in genome sequencing data
iScience, 2022 Summary: Human endogenous retroviruses (HERVs) integrated into the human genome as a result of ancient exogenous infections and currently comprise ∼8% of our genome.Renata Kabiljo, Harry Bowles, Heather Marriott, Ashley R. Jones, Clement R. Bouton, Richard J.B. Dobson, John P. Quinn, Ahmad Al Khleifat, Chad M. Swanson, Ammar Al-Chalabi, Alfredo Iacoangeli +10 moredoaj +1 more sourceAn assessment of bioinformatics tools for the detection of human endogenous retroviral insertions in short-read genome sequencing data
Frontiers in Bioinformatics, 2023 There is a growing interest in the study of human endogenous retroviruses (HERVs) given the substantial body of evidence that implicates them in many human diseases.Harry Bowles, Renata Kabiljo, Renata Kabiljo, Ahmad Al Khleifat, Ashley Jones, John P. Quinn, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Richard J. B. Dobson, Chad M. Swanson, Ammar Al-Chalabi, Ammar Al-Chalabi, Alfredo Iacoangeli, Alfredo Iacoangeli, Alfredo Iacoangeli +15 moredoaj +1 more sourceInteraction of convective organization with monsoon precipitation, atmosphere, surface and sea: The 2016 INCOMPASS field campaign in India
Quarterly Journal of the Royal Meteorological Society, 2019 The INCOMPASS field campaign combines airborne and ground measurements of the 2016 Indian monsoon, towards the ultimate goal of better predicting monsoon rainfall. The monsoon supplies the majority of water in South Asia, but forecasting from days to the A. Turner, G. Bhat, G. Martin, D. Parker, C. Taylor, A. Mitra, S. Tripathi, S. Milton, E. Rajagopal, Jonathan G. Evans, R. Morrison, S. Pattnaik, M. Sekhar, B. Bhattacharya, R. Madan, M. Govindankutty, J. Fletcher, P. Willetts, A. Menon, J. H. Marsham, Kieran M. R. Hunt, T. Chakraborty, Geet George, M. Krishnan, C. Sarangi, D. Belušić, L. Garcia-Carreras, M. Brooks, S. Webster, J. Brooke, C. Fox, R. Harlow, J. Langridge, A. Jayakumar, S. Böing, O. Halliday, J. Bowles, J. Kent, D. O’Sullivan, A. Wilson, C. Woods, S. Rogers, R. Smout‐Day, D. Tiddeman, D. Desai, R. Nigam, S. Paleri, A. Sattar, M. Smith, D. Anderson, S. Bauguitte, R. Carling, C. Chan, S. Devereau, G. Gratton, D. Macleod, G. Nott, M. Pickering, H. Price, S. Rastall, C. Reed, J. Trembath, A. Woolley, A. Volonté, B. New +64 moresemanticscholar +1 more sourceA global reptile assessment highlights shared conservation needs of tetrapods
Nature, 2022 Comprehensive assessments of species’ extinction risks have documented the extinction crisis1 and underpinned strategies for reducing those risks2. Global assessments reveal that, among tetrapods, 40.7% of amphibians, 25.4% of mammals and 13.6% of birds ...N. Cox, B. Young, Philip Bowles, Miguel Fernandez, Julie Marin, G. Rapacciuolo, M. Böhm, T. Brooks, S. B. Hedges, C. Hilton‐Taylor, M. Hoffmann, Richard K. B. Jenkins, M. Tognelli, G. Alexander, A. Allison, N. Ananjeva, M. Auliya, L. Avila, D. G. Chapple, D. Cisneros-Heredia, H. Cogger, G. Colli, Anslem de Silva, C. C. Eisemberg, J. Els, A. Fong G., Tandora D Grant, R. Hitchmough, D. Iskandar, Noriko Kidera, M. Martins, Shai Meiri, N. Mitchell, Sanjay Molur, C. Nogueira, J. Ortíz, Johannes Penner, A. Rhodin, Gilson A. Rivas, Mark‐Oliver Rödel, U. Roll, K. Sanders, G. Santos-Barrera, G. Shea, S. Spawls, B. Stuart, K. Tolley, J. Trape, Marcela A Vidal, P. Wagner, B. Wallace, Yan Xie +51 moresemanticscholar +1 more sourcePredicting post-operative right ventricular failure using video-based deep learning
Nature Communications, 2021 The echocardiogram allows for a comprehensive assessment of the cardiac musculature and valves, but its rich temporally resolved data remain underutilized.Rohan Shad, Nicolas Quach, Robyn Fong, Patpilai Kasinpila, Cayley Bowles, Miguel Castro, Ashrith Guha, Erik E. Suarez, Stefan Jovinge, Sangjin Lee, Theodore Boeve, Myriam Amsallem, Xiu Tang, Francois Haddad, Yasuhiro Shudo, Y. Joseph Woo, Jeffrey Teuteberg, John P. Cunningham, Curtis P. Langlotz, William Hiesinger +19 moredoaj +1 more source
