Results 101 to 110 of about 2,093,284 (296)
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Composing Aspects at Shared Join Points [PDF]
Aspect-oriented languages provide means to superimpose aspectual behavior on a given set of join points. It is possible that not just a single, but several units of aspectual behavior need to be superimposed on the same join point.
Aksit, Mehmet +2 more
core
Approximations and Bounds for (n, k) Fork-Join Queues: A Linear Transformation Approach
Compared to basic fork-join queues, a job in (n, k) fork-join queues only needs its k out of all n sub-tasks to be finished. Since (n, k) fork-join queues are prevalent in popular distributed systems, erasure coding based cloud storages, and modern ...
Li, Jianhui +3 more
core +2 more sources
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Towards an Expressive and Scalable Framework for expressing Join Point Models [PDF]
Join point models are one of the key features in aspectoriented programming languages and tools. They provide\ud software engineers means to pinpoint the exact locations in programs (join points) to weave in advices.
Bergmans, Lodewijk +3 more
core
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Procesamiento de big data en Hadoop usando el repartition join
Programación Matemática y Software, 2015 El objetivo principal de este trabajo es el procesamiento de grandes volúmenes de información, conocidos como big data. Presentamos la implementación del algoritmo repartition join para realizar la operación join en un conjunto grande de datos.
Néstor Iván Escalante Fol +4 more
doaj
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Pricing of Responsive Feeder Transit Considering Competitive Relationships With Bike Sharing
IEEE AccessThe pricing problem for demand-responsive feeder transit (RFT) in competitive relationships with public bicycles in bicycle-sharing systems is investigated from a game-theoretic perspective to establish a feeder program for passengers traveling to and ...
Haiting Tan +3 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source