Results 101 to 110 of about 316,576 (301)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Procesamiento de big data en Hadoop usando el repartition join

open access: yesProgramación Matemática y Software, 2015
El objetivo principal de este trabajo es el procesamiento de grandes volúmenes de información, conocidos como big data. Presentamos la implementación del algoritmo repartition join para realizar la operación join en un conjunto grande de datos.
Néstor Iván Escalante Fol   +4 more
doaj  

Pricing of Responsive Feeder Transit Considering Competitive Relationships With Bike Sharing

open access: yesIEEE Access
The pricing problem for demand-responsive feeder transit (RFT) in competitive relationships with public bicycles in bicycle-sharing systems is investigated from a game-theoretic perspective to establish a feeder program for passengers traveling to and ...
Haiting Tan   +3 more
doaj   +1 more source

EMU enlargement: will Great Britain join? [PDF]

open access: yes
At this moment in time, from all the 27 European Union member states only 13 are involved in the 3rd stage of EMU: the 11 „ founding members” which begun to use the euro from 1999, Greece which has joined the euro zone from 2001, and Slovenia starting ...
Mihai Sebea
core  

Could Austria join the Visegrád Group? [PDF]

open access: yes, 2017
The leader of the Freedom Party of Austria (FPÖ), Heinz-Christian Strache, has previously proposed that Austria could join the Visegrád Group of nations, which currently consists of the Czech Republic, Hungary, Poland, and Slovakia.
Schmidt, Paul
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Towards a new viewpoint on causality for time series

open access: yesESAIM: Proceedings and Surveys, 2015
Causation between time series is a most important topic in econometrics, financial engineering, biological and psychological sciences, and many other fields. A new setting is introduced for examining this rather abstract concept.
Fliess M., Join C.
doaj   +1 more source

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