Results 81 to 90 of about 316,576 (301)

N° 34 — Christian JOIN-LAMBERT [PDF]

, 2000
Join-Lambert Christian, Bernard Danièle, Frank Marie-Thérèse. N° 34 — Christian JOIN-LAMBERT. In: Témoins et acteurs des politiques de l'éducation depuis la Libération. Tome 2 - Inventaire de soixante-six entretiens.
Join-Lambert, Christian, Frank, Marie-Thérèse, Bernard, Danièle   +2 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A multi-objective optimization framework integrating ICSL deep learning for forecasting and scheduling emergency medical supply demand in public health emergencies

Scientific Reports
To address the prediction and allocation challenges of emergency medical supplies during the middle and late stages of major outbreaks, we proposed an end-to-end ICSL deep learning algorithm architecture.
Yanzhi Pang, Shixuan Zhou, Benxiao Lou, Huan Xiong, Kexing Fan, Longtang Ning, Yanfang Pan, Guobin Gu, Xiang Wang, Dan Zhou, Chun Bao   +10 more
doaj   +1 more source

The Text of the Ebla Administrative Account TM.75.G.1443+4287 (ARET I 3 + ARET XII 146)

Asia Anteriore Antica
This article reconstructs an administrative text from two large fragments published in two different volumes of the ARET series: Archivi Reali di Ebla. Testi I, text 3, and Archivi Reali di Ebla. Testi XII, text 146.
Amalia Catagnoti
doaj   +1 more source

Join the club

BMJ, 1998
Join us. And celebrate. You deserve it. You've worked hard, you've passed, and you've got a lot to be proud of. So bring your mum and dad if you want. And your wife or your husband and your kids too if you've got any. There's a bit of a ceremony, an informal supper, and a big welcome for all our new members and their families. Be great to see you all.
openaire   +3 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Spherical Linear Diophantine Fuzzy Graphs: Unleashing the Power of Fuzzy Logic for Uncertainty Modeling and Real-World Applications

Axioms
The theory of spherical linear Diophantine fuzzy sets (SLDFS) boasts several advantages over existing fuzzy set (FS) theories such as Picture fuzzy sets (PFS), spherical fuzzy sets (SFS), and T-spherical fuzzy sets (T-SFS).
Mani Parimala, Saeid Jafari
doaj   +1 more source

Issues of legislation regulation of waste management in the Arctic region of Russia

Российская Арктика, 2019
Accumulation of household waste on specialized and unauthorized landfills is an important problem in the Arctic and the Far North. The solid waste disposal system in the country, based on burying (dumping), burning, recycling, does not fully meet the ...
V. A. Makov
doaj   +1 more source

Query Join Processing over Uncertain Data for Decision Tree Classifiers [PDF]

, 2012
Traditional decision tree classifiers work with the data whose values are known and precise. We can also extend those classifiers to handle data with uncertain information. Value uncertainty arises in many applications during the data collection process.
Dr. V. Yaswanth Kumar
core   +1 more source