Results 101 to 110 of about 46,607 (299)
Exploring the Synergies between Join Point Interfaces and Feature-Oriented Programming [PDF]
, 2015 Feature-oriented programming FOP, and aspect-oriented programming AOP have been used to develop modular software product lines SPL. Both approaches focus on modularizing classes behavior and crosscutting concerns CC.
Leger, Paul +3 more
core
FROM JOIN-IRREDUCIBLES TO DIMENSION THEORY FOR LATTICES WITH CHAIN CONDITIONS [PDF]
, 2002 For a finite lattice L, the congruence lattice Con L of L can be easily computed from the partially ordered set J (L) of join-irreducible elements of L and the join-dependency relation DL on J (L).
Wehrung, Friedrich, FRIEDRICH WEHRUNG
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Mapping the Join Calculus to Heterogeneous Hardware [PDF]
, 2012 As modern architectures introduce additional heterogeneity and parallelism, we look for ways to deal with this that do not involve specialising software to every platform.
Alan Mycroft, Peter Calvert
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Agile Construction and Evolution of Product-Line Architectures [PDF]
, 2012 Software Product Line Engineering (SPLE) has proved to have significant advantages in family-based software development, but also implies the up¬front design of a product-line architecture (PLA) from which individual product applications can be ...
Díaz Fernández, Jessica
core +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Using Shared Virtual Memory for Parallel Join Processing [PDF]
, 1993 In this paper, we show that shared virtual memory, in a shared-nothing multiprocessor, facilitates the design and implementation of parallel join processing algorithms that perform significantly better in the presence of skew than previously proposed ...
Shatdal, Ambuj +3 more
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source