Results 31 to 40 of about 1,296,860 (280)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lightning fast and space efficient inequality joins [PDF]
Proceedings of the VLDB Endowment, 2015 Inequality joins, which join relational tables on inequality conditions, are used in various applications. While there have been a wide range of optimization methods for joins in database systems, from algorithms such as sort-merge join and band join, to various indices such as B + -tree, R
Zuhair Khayyat +7 more
openaire +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
NECSUS, 2017 I will examine the film-viewing experience influenced by ‘Danmu’ (literally barrage), particularly popularised in China by the website Bilibili.com. As a combination of private and public film screening-viewing-transformation systems, Danmu allows the ...
Zhu Yeqi
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Perdus dans l’espace : survivre à la mondialisation dans Gravity et Seul sur Mars
ReS Futurae, 2021 The Martian (2015) and Gravity (2013) join a group of recent maritime disaster films in depicting American individuals struggling to survive in hostile natural environments.
Siobhan Carroll
doaj +1 more source
Flows and joins of metric spaces [PDF]
Geometry & Topology, 2005 We introduce the functor * which assigns to every metric space X its symmetric join *X. As a set, *X is a union of intervals connecting ordered pairs of points in X. Topologically, *X is a natural quotient of the usual join of X with itself. We define an Isom(X)-invariant metric d* on *X. Classical concepts known for H^n and negatively curved manifolds
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
From the “Migration Burden” to Migrants’ Burden: Exile in Malta or the Condition of Inter-jobs
Revue Européenne des Migrations Internationales, 2021 Confronted with a “migration burden” deemed unbearable by the authorities, Malta is seen as one of the emblematic spaces of exclusion of exiles in Europe.
Lucas Puygrenier
doaj +1 more source