Results 101 to 110 of about 1,446,234 (287)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

User Revocation and Joining in the Lattice-based V LR Group Signature

open access: yesБезопасность информационных технологий, 2015
Modified lattice-based V LR group signature is proposed, allowing user’s signature revocation and joining the new group member. This new scheme guarantees selfless anonymity and traceability.
Elena Borisovna Aleksandrova   +1 more
doaj  

Preliminary Study of Ultrasonic Welding as a Joining Process for Electrospun Nanofiber Mats

open access: yesNanomaterials, 2018
Electrospinning can be used to create nanofiber mats for diverse applications, from wound dressings and tissue engineering to filters for medical and biotechnological applications.
Emilia Wirth   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Innovative Surface Treatment Techniques for Carbon Fiber-Based Polymer Matrix Composites

open access: yesSolids
Adhesive bonding has emerged as a promising technology for joining carbon fiber reinforced polymer (CFRP) structures in aircraft, offering advantages over traditional mechanical fastening such as weight reduction and uniform stress distribution.
Mehmet Erdem Iris   +5 more
doaj   +1 more source

Method and apparatus for precision sizing and joining of large diameter tubes Patent [PDF]

open access: yes, 1971
Method and apparatus for precision sizing and joining of large diameter tubes by bulging or constricting overlapping ...
Bennight, J. D., Schwinghamer, R. J.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Method of joining aluminum to stainless steel Patent [PDF]

open access: yes, 1969
Joining aluminum to stainless steel by bonding aluminum coatings onto titanium coated stainless steel and brazing aluminum to aluminum/titanium coated ...
Huschke, E. G., Jr., Nord, D. B.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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