Results 81 to 90 of about 273,034 (266)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Preliminary Study of Ultrasonic Welding as a Joining Process for Electrospun Nanofiber Mats

open access: yesNanomaterials, 2018
Electrospinning can be used to create nanofiber mats for diverse applications, from wound dressings and tissue engineering to filters for medical and biotechnological applications.
Emilia Wirth   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

User Revocation and Joining in the Lattice-based V LR Group Signature

open access: yesБезопасность информационных технологий, 2015
Modified lattice-based V LR group signature is proposed, allowing user’s signature revocation and joining the new group member. This new scheme guarantees selfless anonymity and traceability.
Elena Borisovna Aleksandrova   +1 more
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Effect of Rotational Speed on Mechanical Properties of AA5083/AA6082 Friction Stir Welded T-Joints for Naval Applications

open access: yesMetals
This study evaluates the influence of rotational speed on the mechanical and microstructural properties of T-joints fabricated via friction stir welding (FSW) using dissimilar aluminum alloys, AA5083 and AA6082, for naval applications.
Guido Di Bella   +4 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Introduction of Functional Elements with Double-Sided Self-Pierce Riveting

open access: yesJournal of Manufacturing and Materials Processing
The introduction of functional elements is essential for many industrial components which rely on elements such as bolts, screws, nuts, or clips that are integrated into the workpieces.
Rafael M. Afonso, Luís M. Alves
doaj   +1 more source

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