Results 61 to 70 of about 328,553 (316)
On Forming Characteristics of Hems by Means of Incremental Sheet Forming
Journal of Manufacturing and Materials ProcessingGiven the need for versatile joining processes, form-fit joining is gaining increasing importance. Although it has known limitations and complexity, roller hemming remains widely used due to its flexibility. Here, the novel Incremental Sheet Forming (ISF)
Dennis Steinfels, David Bailly
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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Research progress on laser joining of brittle and transparent materials
Hanjie xuebaoThe joining technology of brittle and transparent materials has been widely applied in aerospace, electronic packaging, and sensor industries. Research on the joining technology of transparent materials holds significant academic and engineering ...
Rui PAN +6 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Recent Progress in the Joining of Titanium Alloys to Ceramics
Metals, 2018 The prospect of joining titanium alloys to advanced ceramics and producing components with extraordinary and unique properties can expand the range of potential applications.
Sónia Simões
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
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A review on solid riveting techniques in aircraft assembling
Manufacturing Review, 2020 Solid riveting is the most widely used joining technique in aircraft assembly, and the current key problems affecting practical application and reliable lifting are concentrated on static strength and fatigue.
Zhao Hongwei +7 more
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