Results 51 to 60 of about 436,548 (250)

Joining Technology Innovations at the Macro, Micro, and Nano Levels

Applied Sciences, 2019
With the growing joining requirements of emergent engineering materials and new applications, conventional welding continues to evolve at all scales spanning from the macro- down to the micro- and nanoscale.
Anming Hu, Jolanta Janczak-Rusch, Tomokazu Sano   +2 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Recent Joining Materials Options for Ceramic Matrix Composites

International Journal of Ceramic Engineering & Science
The urgent need to mitigate climate change has driven the exploration of innovative materials and processes to achieve net‐zero carbon emissions. This work investigates the potential of ceramic matrix composites (CMCs) as alternatives to traditional ...
Valentina Casalegno, Monica Ferraris, Milena Salvo, Carla Malinverni   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells [PDF]

, 2005
Class switch recombination (CSR) is a region-specific, transcriptionally regulated, nonhomologous recombinational process that is initiated by activation-induced cytidine deaminase (AID).
Lennart Hammarström, Hammarström, L,, Lahdesmaki, A, Aleksi Lähdesmäki, Wei Zhou, Andrew R. Gennery, Jones, AM, Michael R. Ehrenstein, Pan-Hammarstrom, Q, Hammarstrom, L, Zhou, W, Gennery, AR, Ehrenstein, MR, Anne-Marie Jones, Richard A. Gatti, Gatti, RA, Qiang Pan-Hammarström   +16 more
core   +1 more source

Joining of Aluminum Alloy AA7075 and Titanium Alloy Ti-6Al-4V through a Friction Stir Welding-Based Process

, 2023
Combining dissimilar parts has become imperative for developing the structures based on lightweight materials, such as metal alloys, polymers or polymer matrix composites, and this has become one of the solutions to reverse the current trend of CO2 ...
Arménio N. Correia, Pedro Moreira, Gonçalo Cipriano, Daniel F. O. Braga, Francisco Dias, Virgínia Infante   +5 more
core   +1 more source

Research progress on laser joining of brittle and transparent materials

Hanjie xuebao
The joining technology of brittle and transparent materials has been widely applied in aerospace, electronic packaging, and sensor industries. Research on the joining technology of transparent materials holds significant academic and engineering ...
Rui PAN, Yinghao FENG, Pei CHEN, Shujun CHEN, Fan JIANG, Jin YANG, Peng LI   +6 more
doaj   +1 more source

On Forming Characteristics of Hems by Means of Incremental Sheet Forming

Journal of Manufacturing and Materials Processing
Given the need for versatile joining processes, form-fit joining is gaining increasing importance. Although it has known limitations and complexity, roller hemming remains widely used due to its flexibility. Here, the novel Incremental Sheet Forming (ISF)
Dennis Steinfels, David Bailly
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source