Results 41 to 50 of about 273,034 (266)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Glass–ceramic joining of duplex SiCf/SiC cladding tubes by localized rapid heating and its interfacial hydrothermal corrosion behavior

Journal of Advanced Ceramics
SiCf/SiC cladding tubes were joined to end plugs using Y2O3–Al2O3–SiO2 (YAS) glass filler through localized rapid induction heating at 1400–1500 °C. The joint fabricated at 1450 °C exhibited a dense and uniform glass–ceramic interlayer with the highest ...
Chuang-Tian Zhan, Kun-Heng Huang, Jia-Pei Chen, Qu Ai, Yu Tian, Li-Xiang Wu, Yun Li, Wei-Ming Guo, Yang Liu, Rong-Kun Yang, Jia-Xiang Xue, Hua-Tay Lin   +11 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Joining Technology Innovations at the Macro, Micro, and Nano Levels

Applied Sciences, 2019
With the growing joining requirements of emergent engineering materials and new applications, conventional welding continues to evolve at all scales spanning from the macro- down to the micro- and nanoscale.
Anming Hu, Jolanta Janczak-Rusch, Tomokazu Sano   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Recent Joining Materials Options for Ceramic Matrix Composites

International Journal of Ceramic Engineering & Science
The urgent need to mitigate climate change has driven the exploration of innovative materials and processes to achieve net‐zero carbon emissions. This work investigates the potential of ceramic matrix composites (CMCs) as alternatives to traditional ...
Valentina Casalegno, Monica Ferraris, Milena Salvo, Carla Malinverni   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Joining the dots

Nature Plants, 2018
It is hypothesized that morphological evolution occurs through a variety of molecular mechanisms. The position and patterning of petal spots in Clarkia evolved through changes to the regulatory region of a gene that encodes a transcriptional activator of pigment synthesis, prompting its control by novel positional cues.
Fattorini, Róisín, Glover, Beverley J
openaire   +4 more sources

Research progress on laser joining of brittle and transparent materials

Hanjie xuebao
The joining technology of brittle and transparent materials has been widely applied in aerospace, electronic packaging, and sensor industries. Research on the joining technology of transparent materials holds significant academic and engineering ...
Rui PAN, Yinghao FENG, Pei CHEN, Shujun CHEN, Fan JIANG, Jin YANG, Peng LI   +6 more
doaj   +1 more source