Results 71 to 80 of about 273,034 (266)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Microgalvanic Corrosion Behavior of Cu-Ag Active Braze Alloys Investigated with SKPFM

Metals, 2016
The nature of microgalvanic couple driven corrosion of brazed joints was investigated. 316L stainless steel samples were joined using Cu-Ag-Ti and Cu-Ag-In-Ti braze alloys.
Armen Kvryan, Kari Livingston, Corey M. Efaw, Kyle Knori, Brian J. Jaques, Paul H. Davis, Darryl P. Butt, Michael F. Hurley   +7 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Joining of CFRTP and aluminum alloy thin plates using ultrasonic vibrations

Mechanical Engineering Journal, 2019
In order to realize light weight structure with multi-materials, this research applied ultrasonic joining method for dissimilar joining. As the joining members, aluminum alloy and CFRTP, CFRP using thermoplastic as base resin are selected because of ...
Kouta WAKUI, Naoto OHTAKE
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effect of Surface Treatment on Tensile Strength of Steel Single Lap Joints Bonded with Double-Sided Acrylic Foam Tapes for Naval Applications

Metals
This study investigated single lap joints in steel used for naval carpentry. The surface was mechanically treated, and then a double-sided acrylic foam tape was applied with varying surface preparation conditions. Specifically, three different conditions
Guido Di Bella, Mohamed Chairi, Antonio Denaro, Adriano Bado   +3 more
doaj   +1 more source

Microstructure and Properties of Porous Si3N4/Dense Si3N4 Joints Bonded Using RE–Si–Al–O–N (RE = Y or Yb) Glasses

Metals, 2017
The joining of porous Si3N4 to dense Si3N4 ceramics has been successfully performed using mixed RE2O3 (RE = Y or Yb), Al2O3, SiO2, and α-Si3N4 powders. The results suggested that the α-Si3N4 powders partly transformed into β-SiAlON and partly dissolved ...
Ling Li, Liangbo Sun, Chunfeng Liu, Xinhua Wang, Xuanzhi Wang, Jie Zhang   +5 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Join the club

BMJ, 1998
Join us. And celebrate. You deserve it. You've worked hard, you've passed, and you've got a lot to be proud of. So bring your mum and dad if you want. And your wife or your husband and your kids too if you've got any. There's a bit of a ceremony, an informal supper, and a big welcome for all our new members and their families. Be great to see you all.
openaire   +3 more sources