Results 61 to 70 of about 2,108,750 (413)

Total Joint Arthroplasty in Patients With an Implanted Left Ventricular Assist Device

Arthroplasty Today, 2023
Left ventricular assist devices (LVADs) may be used as bridge therapy or destination therapy in heart failure patients. Total joint arthroplasty may improve the functional status of patients limited by arthritis.
John H. Rosenberg, MD, Kevin L. Garvin, MD, Curtis W. Hartman, MD, Beau S. Konigsberg, MD   +3 more
doaj   +1 more source

Influence of cementless hip stems on femoral cortical strain pattern depending on their extent of porous coating [PDF]

, 2012
The extent of porous coating of cementless total hip stems is held responsible for radiological periprosthetic changes, the rate of thigh pain, and even its long-term success.
Bader, Rainer, Ellenrieder, Martin, Mittelmeier, Wolfram, Steinhauser, Erwin   +3 more
core   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Patient-reported outcome measures in arthroplasty registries: Report of the Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty RegistriesPart I. Overview and rationale for patient-reported outcome measures

Acta Orthopaedica, 2016
The International Society of Arthroplasty Registries (ISAR) Steering Committee established the Patient-Reported Outcome Measures (PROMs) Working Group to convene, evaluate, and advise on best practices in the selection, administration, and interpretation
Ola Rolfson, Kate Eresian Chenok, Eric Bohm, Anne Lübbeke, Geke Denissen, Jennifer Dunn, Stephen Lyman, Patricia Franklin, Michael Dunbar, Søren Overgaard, Göran Garellick, Jill Dawson, the Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty Registries   +12 more
doaj   +1 more source

Complications in Total Joint Arthroplasties [PDF]

Journal of Clinical Medicine, 2019
Total joint arthroplasties (TJA) are today considered highly successful operations [...]
Enrique Gómez-Barrena, Eduardo García-Rey   +1 more
openaire   +3 more sources

A randomised controlled trial of total hip arthroplasty versus resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint [PDF]

, 2010
Background: Hip replacement (arthroplasty) surgery is a highly successful treatment for patients with severe symptomatic arthritis of the hip joint. For older patients, several designs of Total Hip Arthroplasty have shown excellent results in terms of ...
Achten, Juul, Costa, Matthew L., Edlin, Richard P., Griffin, Damian R., Parsons, Nicholas R.   +4 more
core   +2 more sources

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

Number of Doses of Systemic Antibiotic Prophylaxis May Be Reduced in Cemented Primary Knee Arthroplasty Irrespective of Use of Antibiotic in the Cement: A Multiregistry-Based Meta-Analysis

JBJS Open Access
Background:. The use of systemic antibiotic prophylaxis (SAP) and antibiotic-loaded bone cement (ALBC) is the accepted practice to reduce the risk of periprosthetic joint infection (PJI) in primary total knee arthroplasty (pTKA). However, practice varies
Tesfaye H. Leta, PhD, Richard N. Chang, MPH, Anne Marie Fenstad, MSc, Stein Atle Lie, PhD, Stein Håkon L. Lygre, PhD, Martin Lindberg-Larsen, PhD, Alma B. Pedersen, PhD, Olav Lutro, MD, Jinny Willis, PhD, Chris Frampton, PhD, Michael Wyatt, MD, Serban Dragosloveanu, MD, Andreea E. Vorovenci, MSc, Dan Dragomirescu, MSc, Håvard Dale, PhD, Geir Hallan, PhD, Jan-Erik Gjertsen, PhD, Heather A. Prentice, PhD, Ove Furnes, PhD, Art Sedrakyan, PhD, Elizabeth W. Paxton, PhD   +20 more
doaj   +1 more source

Autologous platelet gel and fibrin sealant enhance the efficacy of total knee arthroplasty: improved range of motion, decreased length of stay and a reduced incidence of arthrofibrosis [PDF]

, 2007
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DEVILEE, RJJ, EVERTS, PAM, KNAPE, JTA, MAHONEY, CB, OOSTERBOS, CJM, SCHATTENKERK, ME, Van Zundert, Adrien   +6 more
core   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source