Results 91 to 100 of about 7,851,053 (324)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
JOINT ATTENTION AND THE IMAGO TRINITATIS
Zygon, 2023 This article incorporates into Christian theological anthropology some recent findings of a school of scientific researchers in the fields of comparative and developmental psychology.
doaj +2 more sources
Segmentation Stability: a Key Component for Joint Attention [PDF]
, 2005 It is now well established that joint attention is a key capability for socially interacting robots (Brooks et al., 1999, Kaplan and Hafner, 2004, Scassellati, 1999, Itti, 2003).
Baillie, Jean-Christophe +1 more
core
Deep Adaptive Attention for Joint Facial Action Unit Detection and Face Alignment
, 2018 Facial action unit (AU) detection and face alignment are two highly correlated tasks since facial landmarks can provide precise AU locations to facilitate the extraction of meaningful local features for AU detection.
K Zhao +9 more
core +1 more source
Modelling the coevolution of joint attention and language [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2012 Joint attention (JA) is important to many social, communicative activities, including language, and humans exhibit a considerably high level of JA compared with non-human primates. We propose a coevolutionary hypothesis to explain this degree-difference in JA: once JA started to aid linguistic comprehension, along with language evolution, communicative
Shuai, L, Gong, T
openaire +4 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Influence of Co-action on a Simple Attention Task: A Shift Back to the Status Quo
Frontiers in Psychology, 2018 There is a growing consensus among researchers that a complete description of human attention and action should include information about how these processes are informed by social context.
Jill A. Dosso +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
An Implexic Genealogical Analysis of the Absurd
HistoriesAccording to some, humanity’s search to answer the question “What is the meaning of life?” fuels the creative fires that forge all of civilization’s great religious, spiritual, and philosophical texts. But how seriously should we take the question?
Brian Lightbody
doaj +1 more source