Results 71 to 80 of about 1,832,084 (347)

Conceptual designs of multi-degree of freedom compliant parallel manipulators composed of wire-beam based compliant mechanisms [PDF]

open access: yes, 2014
This paper proposes conceptual designs of multi-degree(s) of freedom (DOF) compliant parallel manipulators (CPMs) including 3-DOF translational CPMs and 6-DOF CPMs using a building block based pseudo-rigid-body-model (PRBM) approach.
Hao, Guangbo, Li, Haiyang
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Vibration response of a hybrid steel–timber building element with uncertain material and joint parameters [PDF]

open access: hybrid, 2023
Bettina Chocholaty   +4 more
openalex   +1 more source

Iterative building of Barabanov norms and computation of the joint spectral radius for matrix sets

open access: yes, 2010
The problem of construction of Barabanov norms for analysis of properties of the joint (generalized) spectral radius of matrix sets has been discussed in a number of publications.
Kozyakin, Victor
core   +1 more source

Fast, Exact and Multi-Scale Inference for Semantic Image Segmentation with Deep Gaussian CRFs [PDF]

open access: yes, 2016
In this work we propose a structured prediction technique that combines the virtues of Gaussian Conditional Random Fields (G-CRF) with Deep Learning: (a) our structured prediction task has a unique global optimum that is obtained exactly from the ...
Chandra, Siddhartha, Kokkinos, Iasonas
core   +5 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Strategic planning: attracting investments in agro-industrial enterprises

open access: yesВестник университета
Since agriculture is  an important sector of   the Russian economy, the problem of   lack of   capital in   this industry is   still relevant. The article shows that the effective functioning of  agricultural enterprises in   modern conditions of a ...
D. S. Tusin
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Exchangeable Variable Models [PDF]

open access: yes, 2014
A sequence of random variables is exchangeable if its joint distribution is invariant under variable permutations. We introduce exchangeable variable models (EVMs) as a novel class of probabilistic models whose basic building blocks are partially ...
Domingos, Pedro, Niepert, Mathias
core  

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