Results 81 to 90 of about 4,280,845 (355)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang +11 more
wiley +1 more source
Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective We estimated the real‐world cost‐effectiveness of a standardized education and exercise therapy program (GLA:D) compared to usual care (UC) for people managing hip and/or knee osteoarthritis (HKOA). Methods We used a prospective matched cohort design to recruit people (aged >45 years) diagnosed with HKOA who used GLA:D or UC (not on a ...
Darren R. Mazzei +4 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Cognitive impairment (CI) is common in patients with systemic lupus erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elevated serum levels of S100A8/A9 and matrix metalloproteinase 9 (MMP‐9) in patients with SLE and CI.
Carolina Muñoz‐Grajales +18 more
wiley +1 more source
Scientific ReportsThe carbonation of steel slag (SS) can enhance its performance while capturing CO2. The synergistic effect of combining multi-solid waste materials improves SS’s carbon sequestration efficiency, thereby contributing to reduce carbon emissions. This study
Kang Wang +5 more
doaj +1 more source
Refined Study on Free Vibration of a Cable with an Inertial Mass Damper
Applied Sciences, 2019 To accurately predict the optimum supplemental modal damping ratio of the cable and the corresponding size of the inertial mass damper (IMD), combined effects of the cable sag, the cable flexural rigidity, and the boundary conditions on the control ...
Zhihao Wang +4 more
doaj +1 more source
Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Objective Fatigue is a prevalent and debilitating symptom for patients with rheumatoid arthritis (RA). Although patients and rheumatologists often attribute fatigue to inflammation, other factors such as sleep disturbances are frequently overlooked. This study aims to explore the relationship between subjective (self‐reported) and objective (actigraphy
Natalia V. Chalupczak +12 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim +18 more
wiley +1 more source
Lap-joint corrosion of precoated materials for building applications
Surface and Coatings Technology, 2005 The adoption of designs involving the use of lap joints is becoming increasingly common in the building industry. However, precoated steel sheets assembled by lap joints are prone to suffer durability problems associated with this type of joint, such as the premature deterioration of protective coatings (metallic, organic) and accelerated metallic ...
Chico, Belén +5 more
openaire +3 more sources