Results 51 to 60 of about 1,390,207 (300)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2015 This paper proposes a normalized-constrained approach for the joint clearance design of deployable overconstrained Myard 5R mechanism. Firstly, the overconstrained mobility characteristic of Myard 5R mechanism is analyzed, we show that the dimensional ...
Hao SHEN, Hailin HUANG, Tie JI
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Nonlinear Characteristic of Spherical Joints with Clearance
Journal of Aerospace Technology and Management, 2015 Joints in deployable structures can degrade the stiffness and the stability of spacecraft. In this study, the nonlinear stiffness of spherical joints is investigated. The traditional contact model of spherical joints based on non-conforming contact assumption is presented.
Jing, Zhang +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
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Latin American Journal of Solids and StructuresThis work presents an investigation on wear prediction of multibody system including dry revolute clearance joint using a computational methodology. A procedure to analyze multibody system in which wear is present at revolute joints is presented.
Z.F. Bai, H.B. Zhang, Y. Sun
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
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Jixie chuandong, 2012 The solid model of the system of double cardan joint is built through Pro/Engineer,then it is imported into ADAMS to take the dynamic simulation analysis.For the model which does not contain joint clearance,the proper restrain is added according to ...
张辉, 葛文杰, 宁方立, 赵炜
doaj
Analysis of dynamic characteristics for momentum wheel assembly with joint clearance
Advances in Mechanical Engineering, 2018 To study the effects of joint clearance on the dynamic characteristics of the momentum wheel assembly of satellite antennas, the computational dynamic model of momentum wheel assembly is developed in this article, considering influencing factors ...
Qi Wan +4 more
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Adhesion and surface forces in polymer tribology—A review
Friction, 2018 Polymer tribology is a fast growing area owing to increasing applications of polymers and polymer composites in industry, transportation, and many other areas of economy.
Nikolai Myshkin, Alexander Kovalev
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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