Results 101 to 110 of about 1,329,973 (305)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options

Research and Practice in Thrombosis and Haemostasis
Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males. Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and ...
Bülent Zülfikar, Başak Koç, Fahri Şahin, Hatice İlgen Şaşmaz, Kaan Kavaklı, Can Balkan, Ali Bülent Antmen, Sinan Akbayram, Birol Güvenç, Vahap Okan, Emine Türkkan, Canan Albayrak, Davut Albayrak, Nazan Sarper, Tülin Tiraje Celkan, Orhan Ayyıldız, Salih Aksu, Türkan Patıroğlu, Zafer Şalcıoğlu, Adalet Meral Güneş, Yasemin Altuner Torun, Ümran Çalışkan, Hüseyin Tokgöz, Yılmaz Ay, Gül Nihal Özdemir, Mehmet Sönmez, Ekrem Ünal, Ahmet Fayik Öner, Nil Güler, Osman Alphan Küpesiz, Hale Ören, Serap Karaman, Ayşegül Ünüvar, Mehmet Dağlı, Ahmet Muzaffer Demir, Murat Söker, Bülent Alioğlu, Zühre Kaya, Aylin Canbolat Ayhan, Zafer Bıçakçı, Yusuf Ziya Aral, Muhlis Cem Ar   +41 more
doaj   +1 more source

Arthroscopic Rotator Cuff Repair: Double-Row Transosseous Equivalent Suture Bridge Technique

Arthroscopy Techniques, 2016
Following a failed course of conservative management, arthroscopic rotator cuff repair (ARCR) has become the gold standard treatment for patients presenting with symptomatic rotator cuff (RC) tears. Traditionally, the single-row repair technique was used.
Mina Abdelshahed, M.D., Siddharth A. Mahure, M.D., M.B.A., Daniel J. Kaplan, B.A., Brent Mollon, M.D., F.R.C.S.C., Joseph D. Zuckerman, M.D., Young W. Kwon, M.D., Ph.D., Andrew S. Rokito, M.D.   +6 more
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Hemophilic Arthropathy—Pathophysiology and Advances in Treatment

Rheumato
Hemophilia is an X-linked genetic disorder that predominantly affects males, with females typically serving as asymptomatic carriers. Hemophilia A results from a deficiency or dysfunction of coagulation factor VIII, while a deficiency in factor IX causes
Katarina Kovač, Ivan Ljudevit Caktaš, Nataša Kalebota, Porin Perić   +3 more
doaj   +1 more source

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari, Arens Taga, Sonya Ulrike Steele, Ahmet Hoke   +3 more
wiley   +1 more source

Coinfection with Hepatitis C and HIV Is a Risk Factor for Poor Outcomes After Total Knee Arthroplasty

JBJS Open Access, 2017
Background:. As medical management continues to improve, orthopaedic surgeons are likely to encounter a greater proportion of patients who have coinfection with human immunodeficiency virus (HIV) and hepatitis-C virus (HCV). Methods:.
Siddharth A. Mahure, MD, MBA, Joseph A. Bosco, MD, James D. Slover, MD, MSc, Jonathan M. Vigdorchik, MD, Richard Iorio, MD, Ran Schwarzkopf, MD, MSc   +5 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

MBST-exposure opportunities as a monotherapy of chronic dorsalgia [PDF]

Саратовский научно-медицинский журнал, 2017
The aim: to analyze the clinical effect of MBST-exposure monotherapy, a magnetic resonance method, on the pain syndrome caused by degenerative dystrophic changes of vertebral column structures. Material and Methods. 132 patients both male and female with
Levchenko КК, Kitaev IV, Arleninova OV, Zaretskov AV, Adamovich GA, Belonogov VN, Tikhov AA, Chibrikova Yu.A., Biryukova AV.   +8 more
doaj  

Arthroscopic Repair of Hip Labrum With Suture Anchors

Arthroscopy Techniques, 2017
The acetabular labrum and the transverse acetabular ligament form a continuous ring of tissue on the periphery of the acetabulum that provides a seal for the hip joint and increases the surface area to spread load distribution during weight-bearing. When
Kartik Shenoy, M.D., Amos Z. Dai, B.S., Siddharth A. Mahure, M.D., M.B.A., Daniel J. Kaplan, M.D., Brian Capogna, M.D., Thomas Youm, M.D.   +5 more
doaj   +1 more source