Results 81 to 90 of about 678,190 (310)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Retrospective Evaluation of Synovial Chondromatosis with Histopathological and Clinical Features

open access: yesForbes Tıp Dergisi
Objective: Synovial chondromatosis (SC) is a rare, benign condition characterized by the formation of nodular cartilage within the synovium of joints, bursae, or tendon sheaths.
Özden ÖZ   +7 more
doaj   +1 more source

The effects of systemic ozone application and hyperbaric oxygen therapy on avascular necrosis of the femoral head: An experimental study in the vascular deprivation of the rat femoral head model [PDF]

open access: yes
Objectives: This study aims to assess the effects of systemic medical ozone (O3) application and to compare its effects with hyperbaric oxygen (HBO) therapy for preventing avascular necrosis of the femoral head in a rat model.
Yılmaz, Onur   +5 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Arthroscopic capsular release for frozen shoulder

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Objectives: This study was designed to evaluate the results and technical considerations of arthroscopic capsular release of the glenohumeral joint in frozen shoulder disease.\nMethods: Arthroscopic capsular release was performed in 16 patients (11 women,
Sercan Akpinar   +4 more
doaj  

The influence of powerlifting on pain frequency in the musculoskeletal system

open access: yesJournal of Education, Health and Sport, 2019
Introduction Powerlifting consists of exercises (squat, bench press, deadlift) that are corresponding to the three popular movement patterns. Working on proper functioning of muscles involved in these movements should have a positive impact on their ...
Kacper Pajor, Katarzyna Weber-Nowakowska
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

open access: yes
Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein   +11 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Astragalus membranaceus Extract Attenuates Inflammatory Cytokines and Matrix-Degrading Enzymes in Human Chondrocytes: A Novel Nutraceutical Strategy for Joint Health

open access: yesCurrent Issues in Molecular Biology
The dried root extract of Astragalus membranaceus, also known as Astragali radix, is widely used in traditional Chinese medicine for its multiple health benefits and well-established safety profile.
Alessia Mariano   +3 more
doaj   +1 more source

A case of a ganglion cyst originating from the hip joint and surgical outcome

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
Ganglion cysts are the most common soft tissue tumors of the hand, wrist, and foot. However, those originating from the hip joint are not so frequent. This case report presents a 36-year-old woman who complained of pain in the right groin. A diagnosis of
Senol Akman   +3 more
doaj  

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