Results 31 to 40 of about 1,306,129 (354)

Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]

, 2015
Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
core   +3 more sources

Gout of the Temporomandibular Joint: Report of a Case

International Archives of Otorhinolaryngology, 2014
Introduction Gout is an illness characterized by the deposition of monosodium urate crystals in the joints or in soft tissues. The clinical manifestation results from inflammation of limb joints and pain with a rare presentation in the temporomandibular ...
Isaac Nilton Fernandes Oliveira, Renata Caroline Ferreira Gomes, Raiane Rodrigues dos Santos, Thiago de Paula Oliveira, Larissa Loiuse Cândida Pereira, Pietro Mainenti   +5 more
doaj   +1 more source

Degenerative joint disease in cattle and buffaloes in the Amazon region: a retrospective study [PDF]

Pesquisa Veterinária Brasileira, 2014
A retrospective study of the epidemiological and clinic-pathological aspects of cattle and buffaloes with degenerative joint disease (DJD) was conducted in the state of Pará, Brazil. From 1999 to 2014, eleven cattle and 24 buffaloes were evaluated.
José Diomedes Barbosa, Danillo Henrique S. Lima, Alessandra S. Belo-Reis, Cleyton P. Pinheiro, Melina G.S. Sousa, Jenevaldo B. Silva, Felipe M. Salvarani, Carlos Magno C. Oliveira   +7 more
doaj   +1 more source

The social impact of Mseleni Joint Disease

South African Family Practice, 1988
No abstract available.
D. Mann, V.G. Fredlund
doaj   +1 more source

Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

Journal of Immunology Research, 2023
Diffuse alveolar haemorrhage (DAH) is a rapidly developing condition owing to a lack of effective treatment and resulting in a high mortality rate in systemic lupus erythematosus (SLE).
Xinai Han, Xiaoming Zhang, Rui Song, Shiqi Li, Shujing Zou, Quanguang Tan, Tianyang Liu, Shugeng Luo, Zhe Wu, Hongyu Jie, Jinhong Wang   +10 more
doaj   +1 more source

Bayesian joint spatio-temporal analysis of multiple diseases [PDF]

, 2019
In this paper we propose a Bayesian hierarchical spatio-temporal model for the joint analysis of multiple diseases which includes specific and shared spatial and temporal effects.
Fernández-Navarro, Pablo, Gómez-Rubio, Virgilio, López-Abente, Gonzalo, Palmí-Perales, Francisco, Ramis-Prieto, Rebeca   +4 more
core  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

Network-Based Computational Approach to Identify Delineating Common Cell Pathways Influencing Type 2 Diabetes and Diseases of Bone and Joints

IEEE Access, 2020
Developing type 2 diabetes (T2D) can increase patient risk of developing other common diseases and exacerbate their severity, including diseases that affect bone and joints.
Mohammad Ali Moni, M. Babul Islam, Md Rezanur Rahman, Md Rashed-Al-Mahfuz, Md Abdul Awal, Sheikh Mohammed Shariful Islam, Md. Nurul Haque Mollah, Julian M. W. Quinn   +7 more
doaj   +1 more source

Geoadditive Latent Variable Modelling of Child Morbidity and Malnutrition in Nigeria [PDF]

, 2008
Investigating the impact of important risk factors and geographical location on child morbidity and malnutrition is of high relevance for developing countries. Previous research has usually carried out separate regression analyses for certain diseases or
Fahrmeir, Ludwig, Khatab, Khaled
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source