Results 51 to 60 of about 4,125,277 (310)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Are we Measuring Knee Proprioception Correctly? A Case‐Control Study of Joint Reposition Sense and Reflex Latencies for Measuring Proprioception in Knee Hemophilic Arthropathy

Health Science Reports
Background and Aims Knee proprioception deficits have been found in several types of knee injuries using different measurement techniques. In some cases, such as hemophilic arthropathy, such deficits have been largely inferred from the results of gait ...
Pilar Alberola Zorrilla, Rafael Escamilla Ugarte, Sofía Pérez Alenda, Ana Chimeno Hernández, Daniel Sánchez Zuriaga   +4 more
doaj   +1 more source

Histopathological and histomorphometric investigation of the effects of different irrigation solutions on Achilles tendon healing in rats

, 2023
Objectives: This study aimed to examine the effect of irrigation fluids containing povidone-iodine (PVP-I), rifampicin (RF), and chlorhexidine gluconate (CHG) used during surgery on healing on a rat Achilles tendon model.
Karabag, Sevil, Dincel, Yaşar Mahsut, Can, Erdem   +2 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The popliteal surface axis may define hip anteversion

, 2020
Objectives: This study aims to investigate the usability and reliability of our new axis in a three-dimensional modelling work and demonstrate if it is a reproducible method for anteversion measurement that sufficiently correlates with other computed ...
Akkoyunlu, Nuran Sabir, Akman, Alp, Demirkan, Ahmet Fahir, Yörükoğlu, Ali Çağdaş   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Degenerative joint disease in cattle and buffaloes in the Amazon region: a retrospective study [PDF]

Pesquisa Veterinária Brasileira, 2014
A retrospective study of the epidemiological and clinic-pathological aspects of cattle and buffaloes with degenerative joint disease (DJD) was conducted in the state of Pará, Brazil. From 1999 to 2014, eleven cattle and 24 buffaloes were evaluated.
José Diomedes Barbosa, Danillo Henrique S. Lima, Alessandra S. Belo-Reis, Cleyton P. Pinheiro, Melina G.S. Sousa, Jenevaldo B. Silva, Felipe M. Salvarani, Carlos Magno C. Oliveira   +7 more
doaj   +1 more source

Joint diseases in animal paleopathology: Veterinary approach

Macedonian Veterinary Review, 2015
Animal paleopathology is not a very well known scientific discipline within veterinary science, but it has great importance for historical and archaeological investigations.
Oliver Stevanović, , Maciej Janeczek, , Aleksander Chrószcz, Nemanja Marković   +3 more
doaj   +1 more source

Network-Based Computational Approach to Identify Delineating Common Cell Pathways Influencing Type 2 Diabetes and Diseases of Bone and Joints

IEEE Access, 2020
Developing type 2 diabetes (T2D) can increase patient risk of developing other common diseases and exacerbate their severity, including diseases that affect bone and joints.
Mohammad Ali Moni, M. Babul Islam, Md Rezanur Rahman, Md Rashed-Al-Mahfuz, Md Abdul Awal, Sheikh Mohammed Shariful Islam, Md. Nurul Haque Mollah, Julian M. W. Quinn   +7 more
doaj   +1 more source

Translation, reliability, agreement and validity of the Turkish version of Cumulated Ambulation Score in patients with hip fracture [PDF]

, 2020
Objectives: This study aims to translate and investigate the inter-rater reliability, agreement and validity of the Turkish version of the Cumulated Ambulation Score (CAS-TR) in patients with hip fracture.
KURU ÇOLAK, TUĞBA
core   +1 more source