Results 51 to 60 of about 4,302,514 (304)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Health Science ReportsBackground and Aims Knee proprioception deficits have been found in several types of knee injuries using different measurement techniques. In some cases, such as hemophilic arthropathy, such deficits have been largely inferred from the results of gait ...
Pilar Alberola Zorrilla +4 more
doaj +1 more source
, 2009 Bone and joint infections are recognized as difficult-to-treat infections that result in significant morbidity and mortality among patients and increased healthcare costs.
VENDITTI, Mario +8 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Localized pigmented villonodular synovitis in a child knee
, 2017 Pigmented villonodular synovitis is a benign proliferative tumor of the synovium. It is very rare, and most cases occur in the knee joint. In this article, we report a case of localized pigmented villonodular synovitis in the knee joint of a 14- yearold ...
Atik, O. Sahap and Bozkurt, Hasan Huseyin and Ozcan, Efkan and Bahadir, Batuhan and Ucar, Murat and Ogut, Betul and Memis, Leyla
core +2 more sources
Joint diseases in animal paleopathology: Veterinary approach
Macedonian Veterinary Review, 2015 Animal paleopathology is not a very well known scientific discipline within veterinary science, but it has great importance for historical and archaeological investigations.
Oliver Stevanović, +3 more
doaj +1 more source
IEEE Access, 2020 Developing type 2 diabetes (T2D) can increase patient risk of developing other common diseases and exacerbate their severity, including diseases that affect bone and joints.
Mohammad Ali Moni +7 more
doaj +1 more source
Hyaluronan in joint disease [PDF]
Journal of Internal Medicine, 1997 Engström‐Laurent A (University of Umeå, Umeå, Sweden). Hyaluronan in joint disease (Minisymposium: Hyaluronan). J Intern Med 1997; 242: 57–60.Hyaluronan is a major component of synovial fluid. It is synthesized in the joint and partly degraded in joint capsule and partly carried by lymph to lymph nodes and the general circulation.
openaire +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source