Results 51 to 60 of about 1,286,231 (343)

Hydrogen sulfide and inflammatory joint diseases [PDF]

, 2017
[Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with important physiologic functions in
Blanco García, Francisco J, Burguera, Elena F., Meijide-Faílde, Rosa   +2 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Effects of partial wrist arthrodesis on loading at the radiocarpal joints [PDF]

, 2010
The radiocarpal joint plays an important role in the stabilization of the wrist joint. Degenerative diseases such as rheumatoid arthritis can destabilize the joint and compromise the kinematics of the carpal bones.
Gislason, M.K., Nash, D.H., Stansfield, B.W.   +2 more
core  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Biologic treatments in rheumatoid arthritis and juvenile idiopathic arthritis [PDF]

, 2006
A number of biological approaches to the management of inflammtory arthropathies have been explored. These include the development of IL-1 receptor antagonists and TNF antagonists. Four biological agents are currently marketed in Europe.
Borg, Andrew A.
core  

Synergistic Effects of Six Chronic Disease Pairs on Decreased Physical Activity: The SMILE Cohort Study [PDF]

, 2016
Little is known about whether and how two chronic diseases interact with each other in modifying the risk of physical inactivity. The aim of the present study is to identify chronic disease pairs that are associated with compliance or noncompliance with ...
Akker, M.V.D. (Marjan Van Den), Bie, R.A. (Robert) de, Dörenkamp, S. (Sarah), Mesters, I. (Ilse), Schepers, J. (Jan), Teijink, J.A.W. (Joep), Vos, R. (Rein)   +6 more
core   +4 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

The influence of powerlifting on pain frequency in the musculoskeletal system

Journal of Education, Health and Sport, 2019
Introduction Powerlifting consists of exercises (squat, bench press, deadlift) that are corresponding to the three popular movement patterns. Working on proper functioning of muscles involved in these movements should have a positive impact on their ...
Kacper Pajor, Katarzyna Weber-Nowakowska
doaj   +1 more source

Rheumatoid arthritis and post-COVID-19 syndrome

Научно-практическая ревматология, 2022
In the third year of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2, COVID-19) pandemic doctors are encountering a new pathology – post-COVID-19 syndrome (PCS, long covid). Musculoskeletal manifestations are among the most common and may
Ch. T. Baimukhamedov, A. K. Botabekova, G. N. Dossybayeva, Sh. A. Makhmudov   +3 more
doaj   +1 more source

The effect of cigarette smoke exposure on the development of inflammation in lungs, gut and joints of TNFΔARE mice [PDF]

, 2015
The inflammatory cytokine TNF-alpha is a central mediator in many immune-mediated diseases, such as Crohn's disease (CD), spondyloarthritis (SpA) and chronic obstructive pulmonary disease (COPD).
A Churg, A I D'Hulst, A I D'Hulst, A Oberholzer, AN Ananthakrishnan, B Chassaing, BR Vuillemenot, C Ott, Claude A. Cuvelier, D Kontoyiannis, D Kontoyiannis, D Laukens, D Laukens, D Poddubnyy, D Poddubnyy, D Raddatz, D Wendling, Debby Laukens, Dirk Elewaut, E Perry, EM Thomson, G Kollias, G Macdonald, Griet Conickx, Guy F. Joos, Guy G. Brusselle, H Roberts, HS Hreggvidsdottir, J Bagaitkar, J Callhoff, J George, J Karczewski, JC Peng, JJ Peschon, K Chang, K Vermaelen, KA Papadakis, Karlijn Debusschere, Ken R. Bracke, KR Bracke, L Allais, L Arcavi, L Klareskog, Liesbeth Allais, LK Lundblad, LL Dupont, M De Vos, M Montbarbon, Martine De Vos, MF Neurath, P Jacques, P Jacques, P Vassalli, PG Persson, R Matsuda, R Vlahos, R Vlahos, Rebecca De Smet, S Mukhopadhyay, S Suissa, S Tangedal, S Verschuere, S Verschuere, Selvakumar Subbian, SK Biswas, Smitha Kumar, Stephanie Verschuere, Tania Maes, W Strober, Y Arnson   +69 more
core   +3 more sources