Results 61 to 70 of about 12,297,484 (296)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Association of heavy metals exposure with lower blood pressure in the population aged 8–17 years: a cross-sectional study based on NHANES

open access: yesFrontiers in Public Health
BackgroundThe existing evidence regarding the joint effect of heavy metals on blood pressure (BP) in children and adolescents is insufficient. Furthermore, the impact of factors such as body weight, fish consumption, and age on their association remains ...
Yongzhou Liang   +4 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

JOINT PUB 1-01.1 1999 (OBSOLETE) : Compendium of Joint Publications.

open access: yes, 2009
This publication provides a readily available list of all joint publications and a brief synopsis of each. Included is an overview of joint doctrine development, all promulgated joint publications, all joint publications currently under development, and ...
Joint Staff
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

JOINT PUB 4-01.5 1993 (OBSOLETE) : Joint tactics, techniques and procedures for water terminal operations.

open access: yes, 1995
This publication contains joint tactics, techniques, and procedures (JTTP) for the conduct of water terminal operations. It covers command responsibilities and relationships and the planning and execution for the establishment and operation of water ...
Joint Staff
core  

Discontinuities, Imperfections and Defects in Welded Joints and Their Effects on Joint Performance.

open access: yesJournal of the Japan Welding Society, 1992
(1993). Discontinuities, imperfections and defects in welded joints and their effects on joint performance. Welding International: Vol. 7, No. 1, pp. 5-8.
openaire   +2 more sources

The Effect of Joint Custody on Marriage and Divorce [PDF]

open access: yes
Since the 1970s almost all states have introduced a form of joint custody after divorce. We analyze the causal effect of these custody law reforms on the incidence of marriage and divorce.
Martin Halla
core   +2 more sources

Joint effect of modifying selected risk factors on attributable burden of Cardiovascular Diseases

open access: yesInternational Journal of Preventive Medicine, 2013
Background: There are few published studies that consider the joint effect of multiple risk factors on avoidable burden of cardiovascular diseases (CVDs). This study aimed to estimate the joint effect of avoidable burden of multiple risk factors to CVDs.
Fatemeh Khosravi Shadmani   +1 more
doaj  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

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