Results 41 to 50 of about 219,012 (301)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

The waveform inversion of mainshock and aftershock data of the 2006 M6.3 Yogyakarta earthquake

open access: yesGeoscience Letters, 2021
This study comprehensively investigates the source mechanisms associated with the mainshock and aftershocks of the Mw = 6.3 Yogyakarta earthquake which occurred on May 27, 2006.
Hijrah Saputra   +4 more
doaj   +1 more source

Towards 3D joint inversion of full tensor gravity, magnetotelluric and seismic refraction data [PDF]

open access: yes, 2010
EGU2010-4184-2 Joint inversion of different datasets is emerging as an important tool to enhance resolution and decrease inversion artifacts in structurally complex areas.
Heincke, Björn   +4 more
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

A Multi-Objective Optimization Framework for Joint Inversion

open access: yesAIMS Geosciences, 2016
Different geophysical data sets such as receiver functions, surface wave dispersion measurements, and first arrival travel times, provide complementary information about the Earth structure.
Aaron A. Velasco   +2 more
doaj   +1 more source

A Geometric Approach to Joint Inversion with Applications to Contaminant Source Zone Characterization

open access: yes, 2013
This paper presents a new joint inversion approach to shape-based inverse problems. Given two sets of data from distinct physical models, the main objective is to obtain a unified characterization of inclusions within the spatial domain of the physical ...
Abriola, Linda M.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Status and prospects of joint inversion of geophysical electromagnetic data

open access: yes地球与行星物理论评
Geophysical electromagnetic data inversion is a typical underdetermined problem. Due to the limitations of observational data, individual geophysical methods often suffer from significant non-uniqueness and uncertainty, making it challenging to provide ...
Laonao Wei   +4 more
doaj   +1 more source

Joint inversion of Rayleigh wave phase velocity and ellipticity using USArray: Constraining velocity and density structure in the upper crust [PDF]

open access: yes, 2012
Rayleigh wave ellipticity, or H/V ratio, observed on the surface is particularly sensitive to shallow earth structure. In this study, we jointly invert measurements of Rayleigh wave H/V ratio and phase velocity between 24–100 and 8–100 sec period ...
Lin, Fan-Chi   +2 more
core   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

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