Results 51 to 60 of about 77,241 (265)

Welding Residual Stress Analysis and Fatigue Strength Assessment of Multi-Pass Dissimilar Material Welded Joint between Alloy 617 and 12Cr Steel

Metals, 2017
The reliability of welded structure can be evaluated through welding residual stress analysis and fatigue strength assessment. In this study, welding residual stresses of multi-pass dissimilar material welded joint between alloy 617 and 12Cr steel were ...
Hafiz Waqar Ahmad, Jeong Ho Hwang, Ju Hwa Lee, Dong Ho Bae   +3 more
doaj   +1 more source

Computational assessment of disbond growth behaviour in adhesively bonded wide joints or patch repairs for primary airframe structures

Composites Part C: Open Access, 2022
This paper evaluates the applicability of a damage slow growth management strategy to patch repairs or bonded joints of primary aircraft structures established earlier by the authors utilising wide bonded metal joints through a computational study using ...
Veldyanto Tanulia, John Wang, Garth M. Pearce, Alan Baker, B. Gangadhara Prusty   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Performance Analysis of Joint Radar-Communication System Based on FDA-MIMO Radar

IEEE Access
Faced with the increasingly complicated electromagnetic environment, the joint design of radar and communication system has been an effective solution to save spectrum resources and reduce the complexity of system hardware.
Mengjiao Li, Wen-Qin Wang
doaj   +1 more source

On joint numerical ranges and joint normaloids in a $C^{\ast}$-algebra

Tsukuba Journal of Mathematics, 1986
Let A and B be unital C * algebras. The authors observe that every state on \(A\oplus B\) takes the form \(F(a,b)=tf(a)+(1-t)g(b)\) \(0\leq t\leq 1\). This fact is then applied to joint numerical ranges.
K.R., Unni, C, Puttamadaiah
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Optimizing the Voce–Chaboche Model Parameters for Fatigue Life Estimation of Welded Joints in High-Strength Marine Structures

Journal of Marine Science and Engineering, 2022
This work studies the Voce–Chaboche (V–C) material model parameter optimization for high-strength steel welded joints subjected to cyclic loading. The model parameters of each material zone in a S690 steel butt-welded joint were determined using an ...
Alice Petry, Pasquale Gallo, Heikki Remes, Ari Niemelä   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The joint numerical range and the joint essential numerical range

, 2015
Let B(H) denote the algebra of bounded linear operators on a complex Hilbert space H. The (classical) numerical range of T ∈ B(H) is the set W(T) = {〈T x; x〉: x ∈ H; ‖x‖ = 1} Writing T= T_1 + iT_2 for self-adjoint T_1, T_2 ∈ B(H), W(T) can be identified with the set {(〈T_1 x, x〉,〈T_2 x, x〉) : x ∈ H, ‖x‖ = 1}.
openaire   +2 more sources