Results 91 to 100 of about 3,512 (307)

Preliminary Research on Dynamic Hoek–Brown Strength Criterion for Rock Mass

The Hoek–Brown strength criterion is commonly employed to anticipate rock mass failure, considering influential factors including rock mass quality and static stress conditions.
Li, Xing,, Xie, Xiaokun,, Li, Jianchun,, Zhao, Jian,, Zou, Yang,   +4 more
core   +1 more source

Generic thermo-mechanical model for jointed rock masses Generic thermo-mechanical model for jointed rock masses

, 2020
A new nonlinear thermo-mechanical model for heavily jointed rock masses is presented. The model describes poroelasticity, shear-enhaced compaction and brittle-ductile transition in porous dry rocks. The basic input parameters in the model such as elastic
Oleg Vorobiev
core  

Modeling of a jointed rock mass under triaxial conditions

, 2010
One of the most important aspects of designing a structure on or in a rock mass is based on the strength response of a jointed rock mass. Understanding this important aspect, the present study was undertaken to understand the strength response of a ...
SINGH, TN, VERMA, AK
core   +1 more source

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

APPLICATION OF POINT INTERPOLATION METHOD IN JOINTED ROCK MASS

, 2011
In this paper, point interpolation method (PIM) is applied to analyze the nonlinear and elastoplastic behavior of jointed rock masses. PIM is advantageous over the other meshless methods that are based on moving least square (MLS) technique. On the other
M. HAJIAZIZI, M. R. ASHORY
core   +1 more source

Conducting Research to Identify Key Features and Critical Nodes in the Coalescence and Instability of Pre-Fabricated Jointed Rock

Applied Sciences
The instability of jointed rock masses has been a persistent concern in China’s underground geotechnical engineering, particularly regarding rock mass instability triggered by structural activation, such as faulting.
Buchu Zhang, Shichuan Zhang, Baotang Shen, Yangyang Li, Shilong Song, Xuexian Han   +5 more
doaj   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

The characterisation and analysis of in-situ and blasted block-size distributions and the blastability of rock masses.

, 1997
PhDIn this thesis, previous research on discontinuity geometry, in-situ block size distribution (IBSD), blasted block size distribution (BBSD), and blastability of rock mass is discussed.
Lu, Ping
core  

Modeling Underground Structure Vulnerability in Jointed Rock [PDF]

, 2001
The vulnerability of underground structures and openings in deep jointed rock to ground shock attack is of chief concern to military planning and security.
Swift, R., Steedman, D.
core  

Reliability analysis of support strategies in tunnel construction: Insights from geomechanical analysis of jointed rock masses

Results in Earth Sciences
In this study, the dynamics of jointed rock masses in the challenging geological setting of the Himalayas, with a focus on tunneling activities and recommendations of support for jointing rock mass, were investigated. The jointing in Himalayan rocks mass
Naeem Abbas, Kegang Li, Yewuhalashet Fissha, Jitendra Khatti, Merhawi Berhe Geberegergis, N.Rao Cheepurupalli, Blessing Olamide Taiwo, Zemicael Gebrehiwot, Yemane Kide, N. Sri Chandrahas   +9 more
doaj   +1 more source