Results 101 to 110 of about 3,379,584 (355)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Amentoflavone maintaining extracellular matrix homeostasis and inhibiting subchondral bone loss in osteoarthritis by inhibiting ERK, JNK and NF-κB signaling pathways

Journal of Orthopaedic Surgery and Research
Amentoflavone (AF), a plant biflavone isolated from Selaginella sinensis ethanol extract, is characterized by anti-inflammatory and anti-oxidant properties.
Jianhui Liang, Jiawei Hu, Xin Hong, Ming Zhou, Guoming Xia, Liangshen Hu, Song Luo, Kun Quan, Jianbin Yan, Song Wang, Shaoyong Fan   +10 more
doaj   +1 more source

Efeito das variações de temperatura na transferência de cargas em juntas de pavimentos de concreto

Revista IBRACON de Estruturas e Materiais
Medidas de deflexões com o falling weight deflectometer permitiram a avaliação do comportamento de juntas em pavimentos de concreto simples do ponto de vista de sua eficiência de transferência de cargas (LTE).
G. M. Colim, J. T. Balbo, L. Khazanovich
doaj   +1 more source

Scientific Opinion on the substantiation of a health claim related to collagen hydrolysate and maintenance of joints pursuant to Article 13(5) of Regulation (EC) No 1924/2006

EFSA Journal, 2011
Following an application from Gelita AG, submitted via the Competent Authority of Germany, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific substantiation of a health claim related to collagen ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Experimental Study on Waterproofing Properties of Putty-Based Composite Rubber Strip for Underground Post-Tensioned Precast Concrete Structures

International Journal of Concrete Structures and Materials, 2019
The proper assembly of underground precast concrete structures is often critical in the construction of underground structures. In particular, interfacial waterproofing between precast concrete segments is a key factor influencing use, safety, and life ...
Xiang-guo Wu, Xiao-kai Chen, Shi-yan Yu, Seongwon Hong, Thomas H.-K. Kang   +4 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Joint Damage in ANCA-Associated Systemic Vasculitis Message I. Microscopic Polyangiitis

Bolʹ, Sustavy, Pozvonočnik, 2016
Articular syndrome is one of the main signs of the microscopic polyangiitis (MPA), which in some regions of the Earth accounts for over 90 % of all systemic vasculitis (SV), associated with antineutrophil cytoplasmic antibodies (ANCA).
D.V. Pomazan, V.I. Suiarko, Ye.D. Iegudina, T.B. Bevzenko, O.V. Syniachenko   +4 more
doaj   +1 more source

Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug‐Resistant Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To develop a novel deep‐learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug‐resistant epilepsy (DRE) and test if it can screen diverse neurocognitive impairments identified through neuropsychological assessments.
Jeong‐Won Jeong, Min‐Hee Lee, Hiroshi Uda, Yoon Ho Hwang, Michael Behen, Aimee Luat, Csaba Juhász, Eishi Asano   +7 more
wiley   +1 more source

Anesthetic Mechanism of Myeloacupuncture in Joints аnd Spine Pathology

Bolʹ, Sustavy, Pozvonočnik, 2015
The article presents a literature review on the application of such method of reflexotherapy acupuncture as myeloacupuncture used in the pathology of the peri­pheral joints and spine.
V.V. Yakovlenko, V.M. Sokrut, O.V. Syniachenko   +2 more
doaj   +1 more source

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children with Juvenile Idiopathic Arthritis. [PDF]

Arthritis Care Res (Hoboken)
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Vega-Fernandez P, Avar-Aydin PO, Rogers K, Lovell DJ, Huggins J, Grom A, Brunner HI, Schulert GS, Angeles-Han ST, Altaye M, Cassedy A, Meyers AB, Ting TV.   +12 more
europepmc   +2 more sources