Results 21 to 30 of about 884,849 (317)

Key Triggers of Osteoclast-Related Diseases and Available Strategies for Targeted Therapies: A Review

open access: yesFrontiers in Medicine, 2017
Osteoclasts, the only cells with bone resorption functions in vivo, maintain the balance of bone metabolism by cooperating with osteoblasts, which are responsible for bone formation.
Haidi Bi   +7 more
doaj   +1 more source

Structural Behavior of Floor Systems Made by Floor Plates—Mechanical Model Based on Test Results

open access: yesApplied Sciences, 2021
In daily engineering practice, the execution of concrete slabs by the mean of precast floor plates is seen as a common and reliable way to create massive slabs.
Tom Molkens, Ann Van Gysel
doaj   +1 more source

A machine learning approach to predict postoperative sleep disturbance after total knee arthroplasty: a comparative study of multiple algorithms

open access: yesFrontiers in Medicine
BackgroundPostoperative sleep disturbance (PSD) is a common complication following total knee arthroplasty (TKA), which negatively impacts patient recovery.
Yi-xiang Zhang   +12 more
doaj   +1 more source

A Case of Geroderma Osteodysplasticum Syndrome: Unique Clinical Findings

open access: yesGlobal Medical Genetics, 2022
Geroderma osteodysplasticum (GO; MIM 231070) is characterized by a typical progeroid facial appearance, wrinkled, lax skin, joint laxity, skeletal abnormalities with variable degree of osteopenia, frequent fractures, scoliosis, bowed long bones ...
Maha Alotaibi   +3 more
doaj   +1 more source

USE OF ACCELERATED METHODS OF DETECTION OF MULTI-DRUG RESISTANT EXTRAPULMONRY TUBERCULOSIS

open access: yesПаёми Сино, 2018
Objective: To evaluate modern diagnostic methods in identifying extrapulmonary forms of tuberculosis (EPT) with drug resistance. Methods: To examine the time limits and identification of circumstances and diagnostics in EPT considered TB-06 ...
D.K. KOZHOMKULOV   +5 more
doaj   +1 more source

Joints Of Steel Sandwich Structures

open access: yesPolish Maritime Research, 2021
Steel sandwich structures are perceived as alternatives to single-skin welded structures in the shipbuilding industry due its advantages like significant reduction of mass in relation to typical single skin structure.
Kozak Janusz
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Prevalence of Pain and Disability of the Spine and Joints in Selected Types of Sport: Protocol for a Cross-Sectional Study

open access: yesApplied Sciences, 2021
(1) Background: Joint and back pain are enormous and important clinical and public health problems that significantly affect people of all ages. Although the epidemiology of pain in the general population is well documented, less information is available
Alena Buková   +5 more
doaj   +1 more source

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