Results 151 to 160 of about 316,330 (294)

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze   +19 more
wiley   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka   +4 more
wiley   +1 more source

The impact of ERAP1 inhibition on metabolite homeostasis of melanoma cells. [PDF]

open access: yesSci Rep
Raja A   +7 more
europepmc   +1 more source

Review of articular cartilage repair techniques and their application in the horse

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton   +2 more
wiley   +1 more source

All the bedrooms a stage: Reconceptualizing sex as “performance” to sex as “rehearsal”

open access: yesFeminist Anthropology, EarlyView.
Abstract In the United States, sex is often spoken about in terms of performance, and naturally invokes language of theatricality. Sexual performance has been used as an umbrella term to refer to sexual satisfaction, behavior, embodiment, and also pathology in terms of conditions such as erectile dysfunction.
Taylor Harmon
wiley   +1 more source

Queer configurations: The female divine, regional identity, and Queer‐religious belonging in South India

open access: yesFeminist Anthropology, EarlyView.
Abstract This article explores how queerness and religion intersect in a unique enactment of Bathukamma, a flower festival honoring the female divine in Hyderabad, the capital of the South Indian state of Telangana. Drawing on theories of figuration, I analyze how local queer organizations celebrate the festival in a way that engages two distinctive ...
Stefan Binder
wiley   +1 more source

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