Results 41 to 50 of about 19,852 (251)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
still from Same Joke, Different Time [PDF]
, 2016 This is from the final part of the of the Same Joke series. It is entitled Same Joke, Different Time. I am reciting the joke again, this time for thirty minutes without pause. In this work I explore how duration would affect the joke.
Robertson, Drew
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The Joke – a(n) (Un)Important Form of Humor
Etnoantropološki Problemi, 2016 The joke is a form of humor that has not received as much attention by Serbian folkloristics and anthropology as it deserves. A possible reason for this is that the joke is so thoroughly incorporated into everyday communication that it tends to be ...
Vesna Trifunović
doaj
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Verbal humor in selected Indonesian stand up comedian’s discourse: Semantic analysis using GVTH
Cogent Arts & Humanities, 2021 Humor is inevitable and can be found in many aspects of human life. In Indonesia, stand-up comedy (SUC) becomes a trend proven by the existence of some talent competitions in this area.
Mulyadi Mulyadi +2 more
doaj +1 more source
still from Same Joke, Different Shirts [PDF]
, 2016 3This is a still from the video Same Joke, Different Shirts. It is the first in the Same Joke series. I wanted to make works about variation in telling jokes. The series focuses on timing in stand-up comedy, specifically repetition.
Robertson, Drew
core +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source