Results 81 to 90 of about 31,402 (297)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng   +14 more
wiley   +1 more source

joke (talking)

open access: yes, 1984
Kenneth Hepinstall tells a joke while performing at the Blue Ridge Folklife Festival on the Bedford county ...
Hepinstall, Kenneth;
core  

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

open access: yesAdvanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang   +19 more
wiley   +1 more source

NBC News Scripts

open access: yes, 1964
Script from the WBAP-TV/NBC station in Fort Worth, Texas, covering a news story about a a local service station was robbed in Fort Worth; the robber said it was all a ...
WBAP-TV (Television station : Fort Worth, Tex.)
core  

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai   +11 more
wiley   +1 more source

Math Book Joke

open access: yes, 2017
Will: What did one math book say to the other? Katie: What? [Brief pause. He raises his eyebrows.] Will: I’ve got problems. [He waits a moment and then smiles.] Claire: [sarcastically] Ha ha ha.
Francis, Katie
core   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li   +13 more
wiley   +1 more source

ICT and Curriculum Change [PDF]

open access: yes, 2005
The change towards the information society implies that many countries have to change their curricula, because students need to develop competencies that are not addressed in the traditional curricula.
Pelgrum, Hans, Voogt, Joke
core  

Шутливый дискурс как художественно-эстетический феномен (на материале романа в стихах Евгений Онегин А.С. Пушкина)

open access: yesPolilog: Studia Neofilologiczne, 2011
Humorous discurse as an artistic and esthetic phenomenon (based on Eugene Onegin by A.S. Pushkin) The light-hearted (ironic) discourse is interpreted in this article as one of those three criteria that help to distinguish grate literature from mediocre,
Anatolij Andriejew
doaj  

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