Results 81 to 90 of about 316,330 (294)

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

Transforming classroom practices through teachers' learning of TPACK: The case of in-service teachers at Kibasila Secondary School in Tanzania [PDF]

open access: yes, 2012
This study investigated the extent to which teachers’ learning of Technological Pedagogical Content Knowledge (TPACK) has an impact on their technology use and classroom practices.
Fisser, P.H.G.   +2 more
core   +1 more source

On the Moduli Space of SU(3) Seiberg-Witten Theory with Matter

open access: yes, 2002
We present a qualitative model of the Coulomb branch of the moduli space of low-energy effective N=2 SQCD with gauge group SU(3) and up to five flavours of massive matter.
A. Klemm   +6 more
core   +3 more sources

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang   +8 more
wiley   +1 more source

Two sides of the same coin : assessing translation quality in two steps through adequacy and acceptability error analysis [PDF]

open access: yes, 2014
We propose facilitating the error annotation task of translation quality assessment by introducing an annotation process which consists of two separate steps that are similar to the ones required in the European Standard for translation companies EN ...
Daems, Joke   +2 more
core  

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

“I Has Seen Image Macros!” Advice Animals Memes as Visual-Verbal Jokes

open access: yesInternational Journal of Communication, 2016
This essay considers the prevalent but underresearched phenomenon of humorous Internet memes by focusing on Advice Animal image macros, conceptualized as an internally diversified joke genre proliferating across social media.
Marta Dynel
doaj  

Denotacja – humor – tabu

open access: yesMiędzy Oryginałem a Przekładem, 2019
Denotation – Humour – Taboo This analysis takes as its subject jokes about Poles that appeared in two US-American sitcoms: The Big Bang Theory (Teoria wielkiego podrywu) and 2 Broke Girls (Dwie spłukane dziewczyny), as well as their official Polish TV ...
Kwiryna Proczkowska
doaj   +1 more source

Annual report 2002 LBI organic fruit growing research [PDF]

open access: yes, 2002
Overview of projects, project results, funding bodies and partners in 2002 and plans for 2003 Including: SOIL MANAGEMENT * Evaluation of leaf analysis in organic fruit growing as a tool for measuring the uptake of nutrients: Consultants and ...
Bloksma, Joke   +2 more
core  

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

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