Results 31 to 40 of about 24,396 (244)

Globalisation and ethnic jokes: A new look on an old tradition in Belarus and Estonia

open access: yesThe European Journal of Humour Research, 2017
Christie Davies, the renowned humour researcher and a passionate propagator of the comparative method in studying jokes, stressed the necessity of establishing a relationship between two sets of social facts: the jokes themselves on the one hand, and the
Liisi Laineste, Anastasiya Fiadotava
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

“Yo mama so fat we had to run TWO studies”

open access: yesThe European Journal of Humour Research
Two studies examine factors associated with reactions to the popular mother joke format (i.e., jokes denigrating or disrespecting the audience’s mother), both in general (Study 1, n = 167 undergraduates, predominantly White) and for specific jokes ...
Andrew R. Olah   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Sexual jokes at school and students’ life satisfaction: findings from the 2017/18 Swedish Health Behaviour in School-aged Children study

open access: yesBMC Research Notes, 2021
Objective In a previous study we demonstrated that the occurrence of sexual jokes in the class was associated with higher levels of psychological health complaints.
Sara Brolin Låftman   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Les comédiens de stand-up et la preuve par le rire : le récit comme acte cognitif dans Star Wars Canteen 1 & 2 d’Eddie Izzard*

open access: yesCahiers de Narratologie, 2015
A stand-up comedian is a person whose action consists in standing on stage to trigger laughter by telling stories. Stand-up comedy can be defined as a performed conversation between a comedian and her audience.
Guillemette Bolens
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Genre and stylistic markers of Ukrainian folk jokes

open access: yesThe European Journal of Humour Research, 2023
This article focuses on the study of Ukrainian social and domestic folk jokes that contain information about the life of people, their habits, customs, traditions, and relations, and ridicule the weak sides of Ukrainians. The research material comprises
Olena Yemelyanova   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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