Results 51 to 60 of about 7,204,095 (323)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Recomendaciones para estudiantes de Ingeniería y Ciencias Aplicadas en la escritura de Artículos Científicos

Revista Ingeniería, Matemáticas y Ciencias de la Información, 2019
We offer a set of general recommendations addressed to Engineering and Applied Sciences students with the purpose ofimproving their preparation while managing the challenge of communicating science to their peers, general public andthe decision makers ...
MARCO LUIS SALCEDO TOVAR, ELIMAR CARRASQUERO VELÁSQUEZ   +1 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Letter from the editor in chief. World Rabbit Science: Evolution 2008-2012 and new features for 2013

World Rabbit Science, 2012
In the last meeting of the World Rabbit Science Association held in the setting of the 10th World Rabbit Congress (Sept 5, 2012) at Sharm El-Sheikh (Egypt), the Editor-in-chief of the World Rabbit Science presented the last news about the evolution of ...
Juan José Pascual
doaj   +1 more source

Impact Factor: outdated artefact or stepping-stone to journal certification?

, 2012
A review of Garfield's journal impact factor and its specific implementation as the Thomson Reuters Impact Factor reveals several weaknesses in this commonly-used indicator of journal standing.
A Andrade, A Bonillo Perales, A Coleman, A Fassoulaki, A Lomnicki, A Schubert, A Tal, AI Pudovkin, Anonymous, AP Kurmis, AP Kurmis, AR Weale, AW Jones, AW Jones, B Cashore, B Statzner, B Stiftel, B Timuralp, BD Cameron, BM Althouse, C Chen, C Johnson, C McGarty, C Minelli, C Neuhaus, C Scully, CM Ketcham, CP Robert, CR Bain, CW Holsapple, D Ho, D Leutner, D Poomkottayil, D Schoonbaert, D Ugolini, DB Resnik, DB Resnik, DC Greenwood, DE Drew, DN Laband, DR Smith, DW Straub, E Archambault, E Garfield, E Garfield, E Garfield, E Garfield, E Postma, E Wager, EJ Favaloro, EM Sonderstrup-Andersen, EV Bernstam, F Godlee, F Habibzadeh, F Preti, F-T Krell, FJ Bath, FN Dost, G Abramo, G Jacobs, G Knothe, G Lehmkuhl, G Maier, G Racki, G Walter, G Williams, G Winkmann, G Winkmann, G Yu, G Yu, GE Hunt, H Brown, H Goldstein, H Moed, H Sompel Van de, H Xiao, HB Hansen, HF Moed, I Chalmers, I Hames, J Awrey, J Bollen, J Cheek, J Davies, J Horner, J Kapeller, J Mehrad, J Mehrad, J Moller, J Reedijk, J Roberts, J Schopfel, J Woelfel, JA Dempsey, JB Cohen, Jerome K. Vanclay, JJ Ramsden, JK Vanclay, JL Wulff, JM Campanario, JM Campanario, JM Campanario, JP Skovsgaard, JS Kotiaho, JYA Foo, JYA Foo, K Metze, K Simons, K Soreide, KG Altmann, L Bornmann, L Eaton, L Gollogly, L Leydesdorff, L McKeever, L Rieseberg, L Rieseberg, LL Gluud, LL Lange, M Callaham, M Callaham, M Chew, M Driel Van, M Errami, M Errami, M Frank, M Jahangiriana, M Patterson, M Porter, M Rossner, M Rossner, M Taylor, M-J Johnstone, MA Hernan, MA Ruiz, MC Calver, ME Falagas, ME McVeigh, MF Fox, MJ Cobo, MJ Tobin, MV Simkin, N Haslam, N Rezaei-Ghaleh, N Sombatsompop, N Sombatsompop, P Abraham, P Campbell, P Dong, P Jacso, P Jörgensen, P Owlia, PA Lawrence, PA Todd, PA Todd, PC Gøtzsche, PLoS Medicine Editors, PO Seglen, PO Seglen, PO Seglen, R Adler, R Coleman, R Meneghini, R Rousseau, R Rousseau, R Saunders, R Zetterstrom, RA Brumback, RA Brumback, RJ Epstein, RJ Stein, RP Vlosky, RW Glynn, S Butakov, S Chapman, S Lock, S Meyer zu Eissen, S Saha, S Wang, S Woolgar, SE Gwilym, SJ Bensman, SJ Bensman, SJ Bensman, SL Lau, T Braun, TC Ha, TH Berquist, TL Ogden, TN Leeuwen Van, TP Kurmis, TV Perneger, V Barbour, V Kumar, V Larivière, VA Cartwright, W Glänzel, W Glänzel, W Yue, WH Starbuck, WR Schumm, WT Obremskey   +201 more
core   +1 more source

KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini, Rosario Vasta, Alberto Brusati, Francesco Scheveger, Silvia Peverelli, Alessio Maranzano, Alberto Doretti, Francesco Gentile, Eleonora Colombo, Maura Brunetti, Cristina Moglia, Antonio Canosa, Umberto Manera, Maurizio Grassano, Davide Gentilini, Stefano Messina, Federico Verde, Claudia Morelli, John E. Landers, Bryan J. Traynor, Adriano Chiò, Vincenzo Silani, Andrea Calvo, Antonia Ratti, Nicola Ticozzi   +24 more
wiley   +1 more source

Hijacked Journals and Predatory Publishers: Is There a Need to Re-Think How to Assess the Quality of Academic Research?

Walailak Journal of Science and Technology, 2014
During the last 2 years, there has been extensive discussion about “hijacked journals being imposed on the academic world by the huge increase in the number of bogus publishers and spurious websites”.
Mehrdad JALALIAN, Hamidreza MAHBOOBI
doaj   +1 more source

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study assesses the outcomes of immunotherapy discontinuation in patients with relapsing seronegative idiopathic myelitis (SIM), a condition that remains uninvestigated due to its rarity. We reviewed records from 77 patients with relapsing SIM at the National Cancer Center of Korea, focusing on 11 who discontinued treatment after a median ...
Ki Hoon Kim, You‐Ri Kang, Jae‐Won Hyun, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source