Results 41 to 50 of about 1,147,055 (357)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Composing Baldwin’s Joyful Song
James Baldwin Review, 2023 Music lives and breathes through the spaces of much of James Baldwin’s oeuvre. This article introduces a course that features Baldwin’s musical literature and teaches students to compose music inspired by their newfound knowledge of Baldwin.
Rashida K. Braggs +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
The Joyful Life: An Existential-Humanistic Approach to Positive Psychology in the Time of a Pandemic
Frontiers in Psychology, 2021 In the midst of a global pandemic, psychology has a duty to identify dispositional or character traits that can be cultivated in citizens in order to create resiliency in the face of profound losses, suffering and distress.
Brent Dean Robbins
doaj +1 more source
Celebrating the joy of teaching [PDF]
, 2012 I am excited to be writing this article on celebrating teaching, because all too often it feels like research is celebrated more than teaching at the university.
Tulloch, Bridget
core
From the Joy of the Gospel to the Joy of Christ
Ecclesiology, 2016 Many have perceived and reacted to the fresh presentation of the Christian gospel in the pontificate of Francis. It is tempting to read this as a switch in emphasis from content to form, or from ideas to action, and play Benedict XVI off against Francis I: the introverted scholarly theologian followed by the charismatic preacher. Ultimately undermining
openaire +3 more sources
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
ETHNOPEDAGOGICAL VALUE OF THE COMICAL OF THE MORDOVIAN PEOPLE
Интеграция образования, 2016 Introduction: the article explores the folklore’s educational potential and the comical of the Mordovian people in the context of reflection of socio-philosophical categories in it.
Anastasiya A. Osmushina, Oksana P. Ingle
doaj +1 more source
Frontiers in Psychology, 2021 Students’ academic persistence is a critical component of effective online learning. Promoting students’ academic persistence could potentially alleviate learning loss or drop-out, especially during challenging time like the COVID-19 pandemic.
Yurou Wang, Jihong Zhang, Halim Lee
doaj +1 more source