Results 21 to 30 of about 184,958 (210)
Hermeneutic Notion of a Human Being as an Acting and Suffering Person: Thinking with Paul Ricoeur
Ethics in Progress, 2013 Acting and suffering subjectivity makes a grand sujet in Ricoeur's philosophy. In his Time and Narrative Ricoeur created the notion of narrative identity which is an individual internalized and evolving life strory.
Andrew Wiercinski
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The Cultural Impact Emphasizing Divine Traditions in Verse 7 of Surah Ibrahim on Promoting Joy and Hope in Society [PDF]
قرآن فرهنگ و تمدنFostering a spirit of joy and hope in society, with its diverse benefits, leads people to exert efforts with multiplied energy, resulting in comprehensive progress in various fields.
Fatemeh Khashei +2 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
HTS Teologiese Studies/Theological Studies, 2019 Eben Scheffler’s understanding of Luke 24:13–33 enabled us to understand the exegesis of the Old Testament of the past two millennia as a play with words, expressions and interpretations.
Jurie le Roux
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Parsing (malicious) pleasures: Schadenfreude and gloating at others’ adversity
Frontiers in Psychology, 2015 We offer the first empirical comparison of the pleasure in seeing (i.e., schadenfreude) and in causing (i.e., gloating) others’ adversity. In Study 1, we asked participants to recall and report on an (individual or group) episode of pleasure that ...
Colin Wayne Leach +2 more
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The Nature and Pathology of Joy and the Obstacle for knowing it from Viewpoint of Ayatollah Javadi Amoli [PDF]
اخلاق وحیانی, 2019 People intrinsically seek for joy and pleasure, hating toil. Using analytical method, this paper explains the viewpoint of Ayatollah Javadi Amoli concerning joy, its nature, sorts of it, pathology and obstacles for knowing it.
rouhollah shahmoradian +2 more
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